Active video games: the mediating effect of aerobic fitness on body composition
© Maddison et al.; licensee BioMed Central Ltd. 2012
Received: 13 December 2011
Accepted: 3 May 2012
Published: 3 May 2012
Increased understanding of why and how physical activity impacts on health outcomes is needed to increase the effectiveness of physical activity interventions. A recent randomized controlled trial of an active video game (PlayStation EyeToy™) intervention showed a statistically significant treatment effect on the primary outcome, change from baseline in body mass index (BMI), which favored the intervention group at 24 weeks. In this short paper we evaluate the mediating effects of the secondary outcomes.
To identify mediators of the effect of an active video games intervention on body composition.
Data from a two-arm parallel randomized controlled trial of an active video game intervention (n = 322) were analyzed. The primary outcome was change from baseline in BMI. A priori secondary outcomes were considered as potential mediators of the intervention on BMI, including aerobic fitness (VO2Max), time spent in moderate-to-vigorous physical activity (MVPA), and food snacking at 24 weeks.
Only aerobic fitness at 24 weeks met the conditions for mediation, and was a significant mediator of BMI.
Playing active video games can have a positive effect on body composition in overweight or obese children and this effect is most likely mediated through improved aerobic fitness. Future trials should examine other potential mediators related to this type of intervention.
Australian New Zealand Clinical Trials Registry
Study ID number: ACTRN12607000632493
KeywordsActive video games Physical activity Sedentary behavior Children Overweight
Increased understanding of why and how physical activity impacts on health outcomes is needed to increase the effectiveness of physical activity interventions. A recent randomized controlled trial of an active video game (PlayStation EyeToy™) intervention showed a statistically significant treatment effect on the primary outcome, change from baseline in body mass index (BMI), which favored the intervention group at 24 weeks . Active video games are electronic games that allow players to physically interact (using arm, leg, or whole-body movement) with images onscreen in a variety of activities such as sports (e.g., football, boxing, martial arts) and other activities (e.g., dancing, washing windows).
In this short paper we evaluate the mediating effects of the secondary outcomes. Treatment mediators identify possible mechanisms through which a treatment might achieve its effects. These mechanisms are causal links between treatment and outcome .
A two-arm parallel randomized controlled trial was conducted in Auckland, New Zealand from February 2008 to January 2010. 322 overweight and obese children aged 10–14 years, who were current users of sedentary video games were randomly assigned to either receive an active video game intervention (n = 160) or no change (control group; n = 162). Full details of recruitment, participant flow through the study and measures have been published elsewhere [1, 3].
In brief, participants were recruited through schools and various community locations in Auckland city. Eligible participants were aged 10–14 years, overweight or obese (according to the International Obesity Task Force international cut-offs for child obesity) , and owned a PlayStation®2 or 3 gaming console, but no active video games, including EyeToy™ or Nintendo Wii; and played ≧ two hours of video games per week. Participants were excluded if they had contraindications to performing physical activity (such as a medical condition). One child per household was eligible to take part. Dropout from the study was 24% and 17% for the intervention and control groups, respectively.
Intervention participants received an upgrade (hardware and games) of existing gaming technology enabling them to play Sony PlayStation EyeToy™ active video games at home. A selection of active video games (e.g., Play3, Kinetic, Sport, and Dance Factory; Sony) were provided on the basis of being current releases and offering a variety of activity options. Published MET (Metabolic Equivalent) values for these types of games range from 2.0–5.0 [5, 6]. Children were encouraged to meet current physical activity recommendations (60 minutes of moderate to vigorous physical activity on most days of the week)  by supplementing periods of inactivity with active video game play and substituting periods of traditional non-active video game play with the active version. To ensure the sustainability of the intervention  children were sent a package of new active video games at 12 weeks. Active video game play was sustained at higher levels than baseline at both 12 and 24 weeks in intervention participants , suggesting this strategy was successful. The control group continued with their normal video game play. On completion of the study, participants in the control group received the active video games upgrade package at no cost.
All outcomes were measured at baseline 12 and 24 weeks. Anthropometric data (height and weight) were measured using standard practices . Body fat was assessed using standardized bio-electrical impedance analysis procedures  with the ImpediMed DF50 Bioimpedence Monitor (Queensland, Australia). This method has been validated against deuterium dilution and specific prediction equations developed in New Zealand children . Aerobic fitness was assessed using the 20 meter shuttle test [12, 13]. Seven day physical activity was measured objectively using accelerometry , and daily (for seven days) self-reported snack food consumption was assessed using a participant diary developed and tested in a previous pilot study .
The primary outcome was change from baseline in BMI, while percentage body fat was measured as a secondary outcome. A priori secondary outcomes were considered as potential mediators of the intervention effect on BMI and percentage body fat, including aerobic fitness (VO2Max), time spent in moderate-to-vigorous physical activity (MVPA), and food snacking at 24 weeks.
In accordance with the recommendations of Kraemer et al  for testing mediators of treatment effects in randomized clinical trials, hierarchical regression analyses were conducted on the observed participants’ data with change from baseline to 24 weeks in BMI and percentage body fat as the criterion measures. According to Kraemer and colleagues, a mediator must measure an event or change occurring during treatment, and then it must correlate with treatment choice, hence possibly be a result of treatment, and have either a main or interactive effect on the outcome. Their analytic approach differs conceptually from that of Baron and Kenny  in several important ways. According to Kraemer et al. with mediation, demonstration of precedence is required. A mediator occurs during treatment. Similarly, demonstration of correlation is required. They argue that in absence of such criteria, the interpretation of whether a relationship is mediating or moderating is often arbitrary. The analytic model, in contrast to the several linear model proposed by Baron and Kenny, is exactly the same for moderators and mediators. The difference lies in how M (Mediator or Moderator) is defined in terms of time relation to treatment onset and correlation with treatment choice .
Treatment effects with mediator variable VO 2Max
Difference in treatment effect
Change from baseline
Difference in means
Lower 95% C.I.
Upper 95% C.I.
Percentage % Body Fat
Playing active video games can have a positive effect on body composition in overweight or obese children and this effect is most likely mediated through improved aerobic fitness. Consistent with previous research  we found no effect of the intervention on measured physical activity. The lack of effect on measured physical activity might be in part explained by the large variability of physical activity within individuals and low measurement precision of accelerometers to capture non-ambulatory activity. Here aerobic fitness may have served as a proxy measure of increased physical activity. Future trials should examine other potential mediators related to this type of intervention. Such mediators might include attitudes to or preferences for physical activity, or changes in sedentary behaviour. Our study adopted a very pragmatic approach to video game play by allowing the participants as little or as much as they wished; however future studies may find greater utility in prescribing time spent in active gaming for greater effects on aerobic fitness.
Body mass index
Moderate-to-vigorous physical activity
Maximal oxygen consumption
This was an investigator-initiated study funded by a grant from the Health Research Council of New Zealand (07/077B). RM was supported by a Heart Foundation of New Zealand Fellowship. LF was supported by a Tertiary Education Commission Bright Futures Doctoral Scholarship. CNM is supported by the Heart Foundation of New Zealand Senior Fellowship (Grant 1380).
The authors would like to acknowledge the contributing co-investigators, Professor Anthony Rodgers, Ph.D, The George Institute for International Health, Sydney, New South Wales, Australia, Dr Maea Hohepa, Sport and Recreation New Zealand.
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