Prospective association between organic food consumption and the risk of type 2 diabetes: findings from the NutriNet-Santé cohort study

Table 2 Association between the proportion of organic food in the diet and risk of T2D, NutriNet-Santé study, 2014–2019, N = 33,256^*

model	Q1	Q2	Q3	Q4	Q5	P for trend¹	5 points increment	P²
*Total organic food*
Person-years	26,709	27,128	27,218	27,120	26,816
Number of cases	83	72	51	48	39
Model 1³	1.00 (ref)	0.94 (0.69, 1.30)	0.69 (0.48, 0.98)	0.70 (0.48, 1.00)	0.64 (0.43, 0.95)	0.01	0.97 (0.94, 0.99)	0.01
Model 2⁴	1.00 (ref)	0.89 (0.65, 1.23)	0.69 (0.48, 0.98)	0.67 (0.46, 0.96)	0.65 (0.43, 0.97)	0.01	0.97 (0.95, 0.99)	0.02
*Organic plant food*
Person-years	26,733	27,141	27,179	27,239	26,698
Number of cases	83	67	55	40	48
Model 3⁵	1.00 (ref)	0.88 (0.63, 1.21)	0.74 (0.53, 1.05)	0.55 (0.38, 0.81)	0.76 (0.52, 1.10)	0.01	0.97 (0.95, 1.00)	0.03
Model 4⁶	1.00 (ref)	0.83 (0.60, 1.16)	0.75 (0.53, 1.06)	0.52 (0.36, 0.77)	0.77 (0.53, 1.12)	0.01	0.98 (0.95, 1.00)	0.03
*Organic animal food*
Person-years	26,541	27,104	27,236	27,148	26,960
Number of cases	75	58	65	46	49
Model 5⁷	1.00 (ref)	0.81 (0.57, 1.14)	0.93 (0.66, 1.30)	0.68 (0.47, 0.99)	0.84 (0.58, 1.22)	0.19	0.99 (0.96, 1.01)	0.27
Model 6⁸	1.00 (ref)	0.77 (0.54, 1.09)	0.94 (0.67, 1.31)	0.64 (0.44, 0.93)	0.82 (0.56, 1.19)	0.15	0.99 (0.96, 1.01)	0.27

Abbreviation: Q sex-specific quintile
^*Values are Hazard ratio (95% confidence intervals), 5 points correspond to 5% of the contribution of OF to the diet
¹P for trend modeling quintile as ordinal independent variable
²P for continuous independent variable
³Model 1 is adjusted for age (time-scale), gender, familial history of diabetes, physical activity, occupation, marital status, education, monthly income per unit, smoking status, sPNNS-GS2, energy intake and alcohol consumption
⁴Model 2 is model 1 adjusted for body mass index
⁵Model 3 is model 1 adjusted for total plant food consumption
⁶Model 4 is model 3 adjusted for body mass index
⁷Model 5 is model 1 adjusted for total animal food consumption
⁸Model 6 is model 5 adjusted for body mass index

ISSN: 1479-5868