Table 2 Association between different types of screentime and risk of dementia, Parkinson’s disease, depression and multimorbidity status in the UK Biobank Study^a

Dementia

 No. of dementia

2,745

2,097

995

259

788

1,213

1,424

2,671

 Person years

1,535,930

2,859,977

951,815

285,271

1,172,953

1,527,799

1,334,984

1,597,257

 Incidence per 1000 person years

1.79

0.73

1.05

0.91

0.67

0.79

1.07

1.67

 Model 1

1.00 (reference)

0.56 (0.53, 0.60) ^b

0.65 (0.61, 0.70)

0.70 (0.62, 0.80)

1.00 (reference)

1.04 (0.95, 1.14)

1.16 (1.07, 1.27)

1.51 (1.39, 1.63)

 Model 2

1.00 (reference)

0.68 (0.64, 0.72)

0.76 (0.70, 0.82)

0.77 (0.68, 0.88)

1.00 (reference)

1.03 (0.94, 1.13)

1.10 (1.01, 1.21)

1.28 (1.17, 1.39)

Parkinson’s disease

 No. of Parkinson’s disease

1,043

1,265

574

179

487

692

725

1,157

 Person years

1,538,432

2,860,089

951,822

285,167

1,172,991

1,527,860

1,335,623

1,599,036

 Incidence per 1000 person years

0.68

0.44

0.60

0.63

0.42

0.45

0.54

0.72

 Model 1

1.00 (reference)

0.84 (0.78, 0.92)

0.92 (0.83, 1.02)

1.14 (0.97, 1.34)

1.00 (reference)

0.98 (0.87, 1.1)

0.99 (0.89, 1.12)

1.11 (1.00, 1.24)

 Model 2

1.00 (reference)

0.86 (0.79, 0.93)

0.91 (0.82, 1.01)

1.10 (0.94, 1.30)

1.00 (reference)

1.01 (0.9, 1.13)

1.04 (0.92, 1.17)

1.16 (1.03, 1.29)

Depression

 No. of depression

8,136

10,010

4,173

1,381

3,735

5,524

5,433

9,008

 Person years

1,503,163

2,817,435

933,926

278,812

1,156,959

1,504,114

1,312,244

1,560,019

 Incidence per 1000 person years

5.41

3.55

4.47

4.95

3.23

3.67

4.14

5.77

 Model 1

1.00 (reference)

0.69 (0.68, 0.71)

0.88 (0.84, 0.91)

0.98 (0.93, 1.04)

1.00 (reference)

1.09 (1.05, 1.14)

1.20 (1.15, 1.25)

1.62 (1.56, 1.68)

 Model 2

1.00 (reference)

0.85 (0.83, 0.88)

1.00 (0.97, 1.04)

1.07 (1.01, 1.13)

1.00 (reference)

1.08 (1.04, 1.13)

1.13 (1.08, 1.18)

1.35 (1.29, 1.40)

Dementia and Depression Multimorbidity

 No. of disease

575

380

209

50

141

232

272

569

 Person years

1,540,864

2,863,569

953,586

285,734

1,174,372

1,529,909

1,337,485

1,601,987

 Incidence per 1000 person years

0.37

0.13

0.22

0.17

0.12

0.15

0.20

0.36

 Model 1

1.00 (reference)

0.49 (0.42, 0.56)

0.67 (0.57, 0.80)

0.72 (0.54, 0.98)

1.00 (reference)

1.15 (0.91, 1.44)

1.28 (1.02, 1.59)

1.85 (1.50, 2.26)

 Model 2

1.00 (reference)

0.64 (0.55, 0.74)

0.82 (0.68, 0.97)

0.81 (0.60, 1.10)

1.00 (reference)

1.15 (0.92, 1.45)

1.21 (0.96, 1.51)

1.49 (1.21, 1.84)

Parkinson’s disease and Depression Multimorbidity

 No. of disease

218

161

81

26

62

95

124

205

 Person years

1,541,417

2,863,890

953,736

285,752

1,174,546

1,530,074

1,337,682

1,602,493

 Incidence per 1000 person years

0.14

0.06

0.08

0.09

0.05

0.06

0.09

0.13

 Model 1

1.00 (reference)

0.53 (0.42, 0.66)

0.68 (0.52, 0.89)

0.96 (0.64, 1.44)

1.00 (reference)

0.97 (0.69, 1.36)

1.27 (0.92, 1.74)

1.48 (1.09, 2.00)

 Model 2

1.00 (reference)

0.59 (0.47, 0.74)

0.73 (0.55, 0.96)

0.98 (0.65, 1.49)

1.00 (reference)

1.01 (0.72, 1.42)

1.32 (0.95, 1.82)

1.44 (1.05, 1.97)