Table 3 Association between different types of screentime with brain MRI indices in the UK Biobank Studya
MRI indices b | Computer use outside of work, hours/day (0 is reference) | TV viewing time, hours/day (0 to 1 is reference) | ||||
|---|---|---|---|---|---|---|
0.5 to 1 | 2 to 3 | ≥ 4 | 2 | 3 | ≥ 4 | |
White matter hyperintensity volume | ||||||
Model 1 | -0.055 (-0.080, -0.030) c | -0.019 (-0.049, 0.011) | -0.015 (-0.058, 0.028) | -0.002 (-0.025, 0.020) | 0.009 (-0.016, 0.034) | 0.026 (0.000, 0.052) |
Model 2 | -0.042 (-0.067, -0.017) | -0.015 (-0.045, 0.015) | -0.018 (-0.061, 0.025) | -0.006 (-0.028, 0.017) | -0.004 (-0.029, 0.021) | 0.002 (-0.024, 0.029) |
Hippocampal volume | ||||||
Model 1 | 0.090 (0.065, 0.115) | 0.077 (0.047, 0.107) | 0.051 (0.008, 0.094) | -0.020 (-0.042, 0.003) | -0.045 (-0.07, -0.021) | -0.108 (-0.134, -0.082) |
Model 2 | 0.059 (0.034, 0.084) | 0.055 (0.025, 0.085) | 0.034 (-0.009, 0.077) | -0.009 (-0.032, 0.013) | -0.022 (-0.047, 0.003) | -0.067 (-0.094, -0.041) |
Total brain volume | ||||||
Model 1 | -0.013 (-0.036, 0.011) | -0.048 (-0.076, -0.020) | -0.107 (-0.148, -0.066) | 0.048 (0.026, 0.069) | 0.070 (0.047, 0.093) | 0.090 (0.065, 0.114) |
Model 2 | 0.002 (-0.022, 0.026) | -0.022 (-0.050, 0.007) | -0.076 (-0.117, -0.035) | 0.034 (0.013, 0.056) | 0.052 (0.028, 0.075) | 0.072 (0.047, 0.097) |
Total white matter volume | ||||||
Model 1 | -0.022 (-0.049, 0.006) | -0.052 (-0.085, -0.019) | -0.116 (-0.163, -0.069) | 0.022 (-0.002, 0.047) | 0.036 (0.009, 0.063) | 0.039 (0.011, 0.067) |
Model 2 | -0.010 (-0.038, 0.017) | -0.036 (-0.069, -0.003) | -0.097 (-0.145, -0.050) | 0.010 (-0.015, 0.035) | 0.017 (-0.010, 0.044) | 0.017 (-0.013, 0.046) |
Total gray matter volume | ||||||
Model 1 | -0.001 (-0.023, 0.021) | -0.029 (-0.055, -0.003) | -0.065 (-0.103, -0.028) | 0.054 (0.034, 0.073) | 0.076 (0.055, 0.098) | 0.104 (0.081, 0.126) |
Model 2 | 0.012 (-0.010, 0.033) | -0.003 (-0.029, 0.023) | -0.034 (-0.071, 0.003) | 0.044 (0.025, 0.063) | 0.065 (0.043, 0.086) | 0.095 (0.073, 0.118) |