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Table 3 Association of daily eating frequency with mortalities of all-cause, CVD, heart disease and stroke

From: Relationship between circadian eating behavior (daily eating frequency and nighttime fasting duration) and cardiovascular mortality

 

Daily eating Frequency

 

Quintile 1 (< 3 times)

Quintile 2 (3 to 3.5 times)

Quintile 3 (3.5 to 4 times)

Quintile 4 (4 to 4.5 times)

Quintile 5 (4.5 to 6 times)

All-cause mortality

 Death/person-years

1879/108202

759/49470

789/54242

495/35711

635/59486

 Unadjusted

1.67 (1.48–1.89)

1.54 (1.34–1.77)

1.39 (1.21–1.59)

1.44 (1.25–1.66)

1 (ref.)

 Model 1

1.38 (1.21–1.56)

1.30 (1.13–1.49)

1.22 (1.06–1.42)

1.23 (1.06–1.42)

1 (ref.)

 Model 2

1.23 (1.07–1.40)

1.23 (1.07–1.41)

1.16(0.99–1.34)

1.21(1.04–1.39)

1 (ref.)

 Model 3

1.16 (1.01–1.33)

1.20(1.05–1.37)

1.14(0.98–1.33)

1.21(1.04–1.39)

1 (ref.)

CVD mortality

 Death/person-years

797/108202

297/49470

319/54242

181/35711

229/59486

 Unadjusted

2.12 (1.75–2.57)

1.79 (1.44–2.21)

1.72(1.40–2.10)

1.49(1.18–1.88)

1 (ref.)

 Model 1

1.63 (1.33–2.00)

1.41 (1.14–1.75)

1.44 (1.17–1.77)

1.22(0.95–1.56)

1 (ref.)

 Model 2

1.39 (1.12–1.71)

1.28 (1.04–1.59)

1.33 (1.08–1.63)

1.78 (0.92–1.50)

1 (ref.)

 Model 3

1.33 (1.06–1.67)

1.27 (1.02–1.58)

1.32 (1.07–1.63)

1.18 (0.92–1.51)

1 (ref.)

Heart disease-specific mortality

 Death/person-years

512/108202

194/49470

219/54242

113/35711

143/59486

 Unadjusted

2.35 (1.86–2.98)

2.06 (1.57–2.69)

2.07 (1.62–2.64)

1.64 (1.24–2.18)

1 (ref.)

 Model 1

1.87 (1.47–2.39)

1.64 (1.24–2.15)

1.80 (1.41–2.30)

1.36 (1.03–1.81)

1 (ref.)

 Model 2

1.51 (1.17–1.94)

1.44 (1.10–1.89)

1.62 (1.27–2.08)

1.29 (0.98–1.71)

1 (ref.)

 Model 3

1.44 (1.09–1.90)

1.43 (1.08–1.90)

1.62 (1.25–2.10)

1.30 (0.98–1.74)

1 (ref.)

Stroke-specific mortality

 Death/person-years

113/108202

32/49470

45/54242

28/35711

34/59486

 Unadjusted

0.72 (0.48–1.08)

0.77 (0.48–1.21)

1.10 (0.67–1.82)

1.28 (0.94–1.74)

1 (ref.)

 Model 1

0.77 (0.50–1.21)

0.76 (0.47–1.23)

1.10 (0.68–1.77)

1.30 (0.94–1.81)

1 (ref.)

 Model 2

0.89 (0.54–1.48)

0.85 (0.52–1.37)

1.19 (0.73–1.96)

1.39 (0.99–1.91)

1 (ref.)

 Model 3

0.90 (0.52–1.57)

0.89 (0.51–1.57)

1.28 (0.76–2.17)

1.47 (1.04–2.07)

1 (ref.)

  1. Data is weighted HR and 95%CI
  2. Model 1 is unadjusted model with additionally adjusted for age, age, sex, race, education level, annual family income, regular exercise habitus, smoking, drinking, BMI, sleep duration, daily energy intake, AHEI, meal skipping and whether dietary data was surveyed on weekend
  3. Model 2 is model 1 with additionally adjusted for fasting plasma glucose, TG, TC, drug use for controlling glucose/ hypertension/ dyslipidemia, family history of CVD
  4. Model 3 is model 2 with additionally adjusted for nighttime fasting duration