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Table 4 Association of nighttime fasting duration with mortalities of all-cause, CVD, heart disease and stroke

From: Relationship between circadian eating behavior (daily eating frequency and nighttime fasting duration) and cardiovascular mortality

 

Nighttime fasting duration

 

Quintile 1 (≤ 10 h)

Quintile 2 (10 to 11 h)

Quintile 3 (11 to 12 h)

Quintile 4 (12 to 14 h)

Quintile 5 (≥ 14 h)

All-cause mortality

 Death/person-years

1021/78644

673/51160

808/54800

1066/65050

992/55763

 Unadjusted

1.07 (0.94–1.22)

1 (ref.)

1.18 (1.03–1.35)

1.23 (1.08–1.41)

1.38 (1.22–1.58)

 Model 1

1.15 (1.01–1.31)

1 (ref.)

1.15 (1.01–1.32)

1.27 (1.13–1.43)

1.57 (1.39–1.78)

 Model 2

1.16 (1.03–1.32)

1 (ref.)

1.13 (0.99–1.30)

1.23 (1.10–1.39)

1.47 (1.29–1.68)

 Model 3

1.23 (1.08–1.39)

1 (ref.)

1.10 (0.96–1.26)

1.16 (1.04–1.30)

1.36 (1.19–1.54)

CVD mortality

 Death/person-years

388/78644

260/51160

323/54800

433/65050

420/55763

 Unadjusted

1.10 (0.91–1.32)

1 (ref.)

1.25 (1.02–1.54)

1.30 (1.06–1.59)

1.56 (1.30–1.86)

 Model 1

1.19 (0.99–1.42)

1 (ref.)

1.23 (1.01–1.49)

1.30 (1.06–1.59)

1.68 (1.42–1.99)

 Model 2

1.21 (1.01–1.44)

1 (ref.)

1.19 (0.98–1.44)

1.23 (1.00–1.52)

1.52 (1.28–1.80)

 Model 3

1.30 (1.08–1.55)

1 (ref.)

1.15 (0.95–1.39)

1.14 (0.93–1.40)

1.37 (1.12–1.67)

Heart disease-specific mortality

 Death/person-years

255/78644

165/51160

206/54800

276/65050

280/55763

 Unadjusted

1.19 (0.93–1.51)

1 (ref.)

1.32 (1.02–1.72)

1.35 (1.07–1.70)

1.77 (1.41–2.23)

 Model 1

1.27 (1.00–1.62)

1 (ref.)

1.27 (0.99–1.64)

1.35 (1.07–1.70)

1.95 (1.55–2.47)

 Model 2

1.30 (1.02–1.66)

1 (ref.)

1.23 (0.95–1.58)

1.26 (1.00–1.59)

1.72 (1.34–2.19)

 Model 3

1.41 (1.11–1.79)

1 (ref.)

1.18 (0.91–1.52)

1.15 (0.91–1.44)

1.48 (1.12–1.97)

Stroke-specific mortality

 Death/person-years

57/78644

31/51160

43/54800

66/65050

55/55763

 Unadjusted

1.54 (0.95–2.52)

1 (ref.)

1.52 (0.86–2.68)

1.80 (1.06–3.03)

1.77 (1.12–2.79)

 Model 1

1.76 (1.02–3.05)

1 (ref.)

1.49 (0.80–2.76)

1.73 (0.99–3.04)

1.97 (1.22–3.19)

Model 2

1.79 (1.04–3.09)

1 (ref.)

1.44 (0.78–2.68)

1.65 (0.92–2.98)

1.81 (1.09–2.99)

 Model 3

1.89 (1.11–3.23)

1 (ref.)

1.40 (0.75–2.63)

1.59 (0.84–2.98)

1.84 (1.04–3.24)

  1. Data is weighted HR and 95%CI
  2. Model 1 is unadjusted model with additionally adjusted for age, age, sex, race, education level, annual family income, regular exercise habitus, smoking, drinking, BMI, sleep duration, daily energy intake, AHEI, meal skipping and whether dietary data was surveyed on weekend
  3. Model 2 is model 1 with additionally adjusted for fasting plasma glucose, TG, TC, drug use for controlling glucose/ hypertension/ dyslipidemia, family history of CVD
  4. Model 3 is model 2 with additionally adjusted for daily eating frequency