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Table 2 Association of PA and sedentary behavior with risks of POP

From: Accelerometer-measured physical activity, sedentary behavior, and risk of incident pelvic organ prolapse: a prospective cohort study in the UK Biobank

Duration of Activity

Cases/Person-years

Crude HR (95% CI)

Adjusted HR (95% CI)

P for trend

LPA (h/day)

< 4

86/51,172

1 (Reference)

1 (Reference)

< 0.001

4 ~  < 5

255/127,160

1.20 (0.94 to 1.53)

1.23 (0.96 to 1.58)

 

5 ~  < 6

264/126,652

1.25 (0.98 to 1.59)

1.31 (1.03 to 1.68)

 

6 ~  < 7

137/54,007

1.52 (1.16 to 1.99)

1.62 (1.23 to 2.13)

 

 ≥ 7

37/13,088

1.69 (1.15 to 2.48)

1.86 (1.26 to 2.75)

 

MPA (min/day)

 < 30

75/30,608

1 (Reference)

1 (Reference)

0.91

30 ~  < 60

297/124,630

0.99 (0.76 to 1.27)

1.16 (0.90 to 1.50)

 

60 ~  < 90

251/123,393

0.84 (0.65 to 1.09)

1.15 (0.88 to 1.50)

 

90 ~  < 120

109/62,508

0.73 (0.54 to 0.97)

1.10 (0.80 to 1.50)

 

≥ 120

47/30,939

0.63 (0.44 to 0.91)

1.05 (0.72 to 1.55)

 

VPA (min/day)

0

158/62,639

1 (Reference)

1 (Reference)

0.77

> 0 ~  < 5

469/216,292

0.87 (0.72 to 1.04)

1.03 (0.86 to 1.24)

 

5 ~  < 15

125/76,725

0.66 (0.52 to 0.83)

0.96 (0.75 to 1.23)

 

15 ~  < 30

22/13,508

0.66 (0.42 to 1.02)

1.10 (0.70 to 1.75)

 

≥ 30

5/2,916

0.69 (0.28 to 1.69)

1.35 (0.55 to 3.33)

 

Sedentary behavior (h/day)

< 7

82/41,034

1 (Reference)

1 (Reference)

0.15

7 ~  < 8

125/55,033

1.13 (0.86 to 1.49)

1.06 (0.80 to 1.40)

 

8 ~  < 9

174/79,676

1.09 (0.84 to 1.42)

1.00 (0.77 to 1.31)

 

9 ~  < 10

176/83,861

1.05 (0.80 to 1.36)

0.96 (0.73 to 1.24)

 

≥ 10

222/112,475

0.98 (0.76 to 1.26)

0.89 (0.69 to 1.15)

 
  1. The model was adjusted for age when the accelerometry started (year, continuous), ethnicity (White, Black or Black British, Asian or Asian British, or mixed), Townsend deprivation index (continuous), body mass index (kg/m2, continuous), body fat percentage (%, continuous), smoking status (never, previous, or current), menopause status (yes, no, not sure with a history of hysterectomy, or not sure with other reasons), history of hysterectomy (yes or no), and number of births (0, 1, or ≥ 2)
  2. Abbreviations: CI Confidence interval, h Hour, HR Hazard ratio, LPA Light-intensity physical activity, min Minute, MPA Moderate-intensity physical activity, PA Physical activity, POP Pelvic organ prolapse, VPA Vigorous-intensity physical activity