Cost-effectiveness of reducing children’s sedentary time and increasing physical activity at school: the Transform-Us! intervention

Table 2 Modelled trial population cost-effectiveness results, over the lifetime

Metric	PA-I	SB-I
Mean modelled decrease in BMI	Males: 0.55 kg/m² (95% UI 0.12–0.99) Females: 0.43 kg/m² (95% UI 0.09–0.76)	Males: 0.60 kg/m² (95% UI 0.12–1.06) Females: 0.47 kg/m² (95% UI 0.09–0.82)
Mean MET minutes gained per week	N/A	125 (95% UI 65–190)
Total LYs gained over lifetime	78 (95% UI 15–143)	76 (95% UI 12–148)
Total HALYS saved over lifetime	134 (95% UI 26–251)	140 (95% UI 22–259)
Total healthcare cost-savings over lifetime	AUD1.4 M (95% UI AUD276 017-2.6 M)	AUD1.5 M (95% UI AUD246 485-2.8 M)
Total intervention costs	AUD19 759 (95% UI AUD19 452 − 20 094)	AUD32 380 (95% UI AUD32 174 − 32 579)
Total net cost^a	AUD-1.4 M (95% UI AUD-2.6 M to -256,069)	AUD-1.5 M (95% UI AUD-2.8 M to -214,066)
Net cost per HALY saved (ICER)^a	AUD-10 442 (95% UI AUD-8 883 to -11,863)	AUD-10 672 (95% UI AUD-8 772 to -12 329)
Overall result	Dominant^b (95% UI dominant-dominant)
Probability of cost-effectiveness	99.5%	99.2%

Table notes:^a Negative total net costs equate to cost-savings. ^b Dominant interventions result in health gains and cost-savings. ^c The willingness-to-pay threshold for this analysis is AUD50,000 per HALY. Costs are presented in 2010 Australian dollars. 95% UI = 95% uncertainty interval based on 2,000 simulations. AUD = Australian dollars. BMI = body mass index. HALYs = Health adjusted life years. ICER = Incremental cost-effectiveness ratio. Kg = kilograms. LYs = life years. m = metres. M = million. MET = metabolic equivalent task. N/A = not applicable. PA-I = physical activity intervention. SB-I = sedentary behaviour intervention

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