Analysis
a
|
Sample size per group
|
ΔC (95% CI)
|
ΔE (95% CI)
| |
Distribution in CE plane (%)
|
---|
|
Control
|
Phone
|
Euros
|
Weight loss (kg)
|
ICER
|
NE
b
|
SE
c
|
SW
d
|
NW
e
|
---|
Main
|
448
|
453
|
352 (−462; 1095)
|
0.3 (−0.6; 1.3)
|
1009
|
65
|
14
|
6
|
16
|
Complete cases
|
134
|
147
|
593 (−157; 1458)
|
1.1 (−0.02; 2.2)
|
543
|
91
|
7
|
0
|
2
|
Company perspective
|
448
|
453
|
270 (−525; 997)
|
0.3 (−0.6; 1.3)
|
772
|
62
|
17
|
7
|
13
|
| | | |
QALY
|
ICUR
| | | | |
Main
|
448
|
453
|
352 (−490; 1099)
|
0.001 (−0.03; 0.03)
|
245,242
|
41
|
14
|
5
|
40
|
Complete cases
|
120
|
140
|
423 (−458; 1250)
|
0.006 (−0.04; 0.05)
|
131,863
|
50
|
13
|
3
|
34
|
Company perspective
|
448
|
453
|
270 (−525; 997
|
0.001 (−0.03; 0.03)
|
187,545
|
37
|
17
|
8
|
38
|
UK tariff
|
448
|
453
|
352 (−490; 1099)
|
0.007 (−0.04;0.05)
|
52,496
|
50
|
13
|
7
|
30
|
- a In the analysis ΔC= mean difference in total costs, ΔE= mean difference in outcome, ICER (ICUR) =incremental cost-effectiveness (utility) ratio calculated as ΔC/ΔE. In the main analysis missing data were multiply imputed. The complete cases analysis was restricted to participants with complete cost and effect data. b Northeast quadrant of the CE-plane: the intervention is more effective and more costly than self-help brochures. c Southeast quadrant of the CE-plane: the intervention is more effective and less costly than self-help brochures. d Southwest quadrant of the CE-plane: the intervention is less effective and less costly than self-help brochures. e Northwest quadrant of the CE-plane: the intervention is less effective and more costly than self-help brochures.