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Table 4 Associations of weight change during intervention with changes in blood pressure and HbA1c

From: Effects of meal preparation training on body weight, glycemia, and blood pressure: results of a phase 2 trial in type 2 diabetes

 

Weight Loss Increment

 

n

−2.5%

95% CI [ m]

All with final assessment

   

Change in systolic blood pressure, mm Hg

   

Weight change

53

−3.4

−5.4, -1.5

Weight change + age + sex + ethnicity + insulin use + season

52

−3.5

−5.5, -1.4

Weight change + step change + age + sex + ethnicity + season

41

−4.1

−6.1, -2.2

Change in diastolic blood pressure, mm Hg

   

Weight change

53

−2.5

−3.7, -1.2

Weight change + age + sex + ethnicity + insulin use + season

52

−2.3

−3.6, -0.9

Weight change + step change + age + sex + ethnicity + season

41

−2.5

−3.9, -1.0

Change in HbA1c, %

   

Weight change

51

−0.3

−0.4, -0.2

Weight change + age + sex + ethnicity + insulin use + season

50

−0.3

−0.4, -0.2

Weight change + step change + age + sex + ethnicity + season

39

−0.3

−0.4, -0.2

Without antihypertensive medication changes

   

Change in systolic blood pressure, mm Hg

   

Weight change

42

−3.2

−5.5, -1.0

Weight change + age + sex + ethnicity + insulin use + season

42

−3.5

−5.9, -1.1

Weight change + step change + age + sex + ethnicity + season

31

−4.2

−6.5, -2.0

Change in diastolic blood pressure, mm Hg

   

Weight change

42

−2.4

−3.8, -1.0

Weight change + age + sex + ethnicity + insulin use + season

42

−2.2

−3.8, -0.6

Weight change + step change + age + sex + ethnicity + season

31

−2.4

−4.1, -0.7

Without antihyperglycemic medication changes

   

Change in HbA1c, %

   

Weight change

32

−0.3

−0.4, -0.2

Weight change + age + sex + ethnicity + insulin use + season

32

−0.3

−0.4, -0.2

Weight change + step change + age + sex + ethnicity + season

25

−0.3

−0.4, -0.2

  1. m 95% confidence intervals.