Table 5 Associations between quartiles of liking for fat, fat-and-salt and fat-and-sweet sensations, liking for sweet taste and natural sweetness and obesity risk from multivariate Cox proportional hazards model, n = 24,776

 Base model

1.42 (0.85;2.37)

2.29 (1.29;3.77)

2.39 (1.39;4.11)

0.0005

1.29 (0.98;1.70)

1.41 (1.06;1.89)

2.02 (1.51;2.71)

<0.0001

 Model assessing the mediating effect ^d

1.26 (0.75;2.10)

2.01 (1.21;3.32)

1.96 (1.13;3.41)

0.006

/

22

31

32

1.18 (0.90;1.56)

1.23 (0.92;1.65)

1.63 (1.21;2.20)

0.002

/

/

38

52

 Fully adjusted model ^e

1.24 (0.74;2.07)

1.99 (1.20;3.29)

1.85 (1.07;3.23)

0.01

36

1.20 (0.91;1.57)

1.22 (0.91;1.62)

1.49 (1.09;2.00)

0.015

72

 Base model

1.71 (1.01;2.91)

2.40 (1.39;4.12)

2.68 (1.50;4.81)

0.0007

1.52 (1.16;2.00)

1.42 (1.06;1.91)

1.41 (1.02;1.95)

0.11

 Model assessing the mediating effect

1.45 (0.85;2.51)

2.02 (1.16;3.50)

2.13 (1.17;3.88)

0.008

/

27

40

41

1.39 (1.06;1.84)

1.25 (0.93;1.69)

1.16 (0.83;1.62)

0.76

/

/

/

34

 Fully adjusted model

1.36 (0.79;2.33)

1.95 (1.12;3.40)

2.06 (1.13;3.78)

0.009

44

1.44 (1.09;1.90)

1.32 (0.98;1.79)

1.17 (0.84;1.64)

0.68

18

 Base model

1.06 (0.66;1.68)

0.93 (0.56;1.54)

1.14 (0.68;1.91)

0.69

1.04 (0.79;1.37)

1.29 (0.97;1.71)

1.68 (1.25;2.24)

<0.0001

 Model assessing the mediating effect

1.12 (0.70;1.78)

0.97 (0.58;1.60)

1.13 (0.67;1.91)

0.82

/

/

/

16

1.02 (0.77;1.35)

1.24 (0.93;1.64)

1.57 (1.18;2.11)

0.0006

/

/

16

22

 Fully adjusted model

1.09 (0.68;1.74)

0.95 (0.57;1.57)

1.04 (0.61;1.76)

0.95

54

1.01 (0.76;1.33)

1.14 (0.86;1.52)

1.37 (1.02;1.84)

0.02

63

 Base model

0.66 (0.42;1.03)

0.64 (0.40;1.01)

0.51 (0.31;0.83)

0.01

0.85 (0.66;1.09)

0.85 (0.65;1.10)

0.72 (0.54;0.96)

0.035

 Model assessing the mediating effect

0.69 (0.43;1.08)

0.74 (0.46;1.17)

0.56 (0.33;0.94)

0.056

/

/

10

31

0.94 (0.73;1.21)

0.96 (0.74;1.26)

0.86 (0.64;1.15)

0.38

/

/

/

76

 Fully adjusted model

0.74 (0.47;1.16)

0.76 (0.47;1.21)

0.59 (0.35;0.99)

0.08

45

0.92 (0.71;1.18)

0.93 (0.71;1.21)

0.82 (0.61;1.10)

0.23

63

 Base model

0.83 (0.55;1.23)

0.51 (0.32;0.81)

0.44 (0.27;0.71)

0.002

0.73 (0.57;0.92)

0.66 (0.52;0.84)

0.50 (0.39;0.65)

<0.0001

 Model assessing the mediating effect

0.94 (0.63;1.41)

0.66 (0.41;1.05)

0.63 (0.38;1.04)

0.15

/

/

/

66

0.82 (0.64;1.03)

0.80 (0.63;1.03)

0.66 (0.51;0.87)

0.03

/

/

32

68

 Fully adjusted model

0.92 (0.62;1.39)

0.69 (0.43;1.10)

0.62 (0.37;1.04)

0.20

70

0.83 (0.66;1.06)

0.84 (0.66;1.08)

0.69 (0.53;0.91)

0.07

74