Table 4 Depression and other health status as mediators in the association between chronic conditions and low physical activity among older adults (aged ≥50 years)

Angina

Depression

1.17 [1.05–1.29]

0.0040

1.12 [1.01–1.25]

0.0283

1.04 [1.02–1.05]

<0.0001

23.5

Mobility

1.16 [1.05–1.28]

0.0050

1.01 [0.91–1.12]

0.8970

1.15 [1.12–1.18]

<0.0001

95.3

Pain/discomfort

1.18 [1.06–1.30]

0.0015

1.06 [0.96–1.17]

0.2790

1.11 [1.08–1.15]

<0.0001

65.9

Sleep/energy

1.17 [1.06–1.30]

0.0021

1.09 [0.99–1.21]

0.0868

1.07 [1.05–1.10]

<0.0001

43.7

Arthritis

Depression

1.19 [1.07–1.33]

0.0018

1.16 [1.04–1.30]

0.0067

1.02 [1.01–1.04]

<0.0001

13.7

Mobility

1.20 [1.07–1.34]

0.0016

1.06 [0.94–1.19]

0.3286

1.13 [1.10–1.16]

<0.0001

67.8

Pain/discomfort

1.18 [1.06–1.32]

0.0027

1.06 [0.95–1.19]

0.3142

1.12 [1.08–1.15]

<0.0001

64.9

Sleep/energy

1.18 [1.06–1.32]

0.0024

1.13 [1.01–1.26]

0.0377

1.05 [1.03–1.07]

<0.0001

30.2

Asthma

Depression

1.55 [1.29–1.85]

<0.0001

1.50 [1.25–1.79]

<0.0001

1.03 [1.02–1.05]

0.0002

7.6

Mobility

1.52 [1.29–1.78]

<0.0001

1.34 [1.14–1.57]

0.0004

1.13 [1.10–1.17]

<0.0001

30.3

Pain/discomfort

1.55 [1.31–1.84]

<0.0001

1.44 [1.22–1.70]

<0.0001

1.08 [1.05–1.11]

<0.0001

17.3

Sleep/energy

1.56 [1.31–1.86]

<0.0001

1.48 [1.24–1.76]

<0.0001

1.05 [1.03–1.08]

<0.0001

11.8

Diabetes

Depression

1.48 [1.27–1.74]

<0.0001

1.45 [1.24–1.69]

<0.0001

1.03 [1.01–1.04]

0.0004

6.8

Mobility

1.54 [1.32–1.80]

<0.0001

1.35 [1.15–1.57]

0.0002

1.14 [1.11–1.18]

<0.0001

31.2

Pain/discomfort

1.51 [1.29–1.76]

<0.0001

1.40 [1.20–1.64]

<0.0001

1.08 [1.05–1.10]

<0.0001

17.6

Sleep/energy

1.51 [1.29–1.76]

<0.0001

1.44 [1.24–1.68]

<0.0001

1.05 [1.03–1.07]

<0.0001

11.2

Edentulism

Depression

1.20 [1.04–1.40]

0.0143

1.19 [1.03–1.38]

0.0217

1.01 [1.00–1.02]

0.0110

6.7

Mobility

1.25 [1.07–1.46]

0.0041

1.23 [1.05–1.43]

0.0090

1.02 [1.00–1.04]

0.0281

8.7

Pain/discomfort

1.20 [1.04–1.39]

0.0142

1.18 [1.02–1.37]

0.0264

1.02 [1.01–1.03]

0.0051

9.2

Sleep/energy

1.20 [1.04–1.39]

0.0137

1.19 [1.03–1.38]

0.0204

1.01 [1.00–1.02]

0.0141

5.9

Hearing problem

Depression

1.43 [1.22–1.67]

<0.0001

1.39 [1.19–1.64]

<0.0001

1.02 [1.01–1.04]

0.0005

6.3

Mobility

1.52 [1.30–1.78]

<0.0001

1.37 [1.17–1.60]

0.0001

1.11 [1.08–1.14]

<0.0001

25.6

Pain/discomfort

1.52 [1.31–1.76]

<0.0001

1.42 [1.23–1.65]

<0.0001

1.07 [1.04–1.09]

<0.0001

15.5

Sleep/energy

1.47 [1.26–1.73]

<0.0001

1.42 [1.21–1.66]

<0.0001

1.04 [1.02–1.06]

<0.0001

10.0

Tuberculosis

Depression

1.35 [0.98–1.86]

0.0689

1.27 [0.92–1.76]

0.1480

1.06 [1.03–1.10]

0.0008

20.2

Mobility

1.37 [0.99–1.88]

0.0553

1.21 [0.88–1.66]

0.2472

1.13 [1.07–1.20]

<0.0001

39.7

Pain/discomfort

1.39 [1.01–1.90]

0.0412

1.28 [0.93–1.75]

0.1283

1.09 [1.05–1.13]

<0.0001

25.4

Sleep/energy

1.40 [1.01–1.92]

0.0409

1.32 [0.96–1.81]

0.0929

1.06 [1.03–1.09]

0.0001

17.6

Visual impairment

Depression

2.12 [1.61–2.77]

<0.0001

2.04 [1.55–2.67]

<0.0001

1.04 [1.02–1.06]

0.0006

5.1

Mobility

2.10 [1.60–2.77]

<0.0001

1.67 [1.27–2.20]

0.0002

1.26 [1.20–1.32]

<0.0001

30.9

Pain/discomfort

2.10 [1.61–2.75]

<0.0001

1.84 [1.41–2.40]

<0.0001

1.14 [1.10–1.19]

<0.0001

17.9

Sleep/energy

2.12 [1.62–2.77]

<0.0001

1.92 [1.47–2.50]

<0.0001

1.11 [1.07–1.15]

<0.0001

13.4

Multimorbidity

Depression

1.37 [1.23–1.54]

<0.0001

1.32 [1.18–1.48]

<0.0001

1.04 [1.02–1.06]

<0.0001

12.5

Mobility

1.36 [1.22–1.52]

<0.0001

1.14 [1.02–1.29]

0.0236

1.19 [1.15–1.23]

<0.0001

56.4

Pain/discomfort

1.38 [1.24–1.54]

<0.0001

1.22 [1.09–1.36]

0.0006

1.13 [1.09–1.18]

<0.0001

38.7

Sleep/energy

1.37 [1.23–1.53]

<0.0001

1.28 [1.15–1.43]

<0.0001

1.07 [1.04–1.10]

<0.0001

21.6