| Entire sample | Normal weight | Overweight | Obese | P | Non-insulin resistant | Insulin resistant | P |
---|---|---|---|---|---|---|---|---|
n | 396 | 79 | 189 | 128 | Â | 293 | 97 | Â |
Age (years) | 59.58 ± 5.46 | 58.51 ± 5.43 | 59.73 ± 5.45 | 59.58 ± 5.43 | 0.13 | 59.49 ± 5.48 | 59.83 ± 5.44 | 0.61 |
Male (%) | 46 | 64.6 | 54.5 | 46.9 | 0.046 | 41.7 | 56.7 | 0.01 |
BMI (kg/m2) | 28.86 ± 4.55 | 23.25 ± 1.54 | 27.77 ± 1.35 | 33.95 ± 3.61 | 0.000 | 27.54 ± 3.61 | 32.85 ± 4.86 | 0.000 |
Waist (cm) | 96.27 ± 13.39 | 82.80 ± 8.24 | 93.51 ± 0.00 | 108.70 ± 10.85 | 0.000 | 92.56 ± 12.04 | 107.29 ± 11.29 | 0.000 |
HOMA-IR | 2.96 ± 3.25 | 1.49 ± 0.95 | 2.14 ± 1.50 | 5.11 ± 4.72 | 0.000 | 1.68 ± 0.80 | 6.87 ± 4.56 | 0.000 |
Inflammatory profiles | ||||||||
 C3 (mg/dL) | 136.40 (120.30, 152.09) | 115.68 (108.12, 138.27) | 134.72 (121.63, 149.40) | 147.60 (132.70, 166.90) | 0.000 | 130.89 (115.87, 145.20) | 152.52 (137.23,173.53) | 0.000 |
 CRP (ng/mL) | 1.35 (0.99, 2.36) | 1.02 (0.78, 1.55) | 1.34 (1.03, 2.21) | 1.68 (1.10, 3.06) | 0.000 | 1.29 (0.97, 1.90) | 1.95 (1.16, 3.34) | 0.000 |
 IL-6 (pg/mL) | 1.78 (1.19, 2.97) | 1.30 (0.90, 2.06)) | 1.67 (1.13, 2.62) | 2.42 (1.63, 3.76) | 0.000 | 1.53 (1.09, 2.53) | 2.54 (1.69, 3.78) | 0.000 |
 TNF(pg/mL) | 5.86 (4.73, 7.18) | 5.67 (4.40, 7.10) | 5.79 (4.67, 7.04) | 6.05 (4.94, 7.82) | 0.140 | 5.55 (4.59, 6.80) | 6.89 (5.66, 8.65) | 0.000 |
 Leptin (ng/mL) | 2.03 (1.25, 3.16) | 1.38 (0.75, 2.00) | 2.00 (1.14, 2.75) | 3.01 (1.90, 4.87) | 0.000 | 1.89 (1.14, 2.74) | 2.78 (1.55,4.92) | 0.001 |
 ACDC (ng/mL) | 4.86 (2.86, 7.54) | 7.46 (3.89, 10.27) | 5.03 (3.17, 7.65) | 3.80 (2.45, 5.81) | 0.000 | 5.48 (3.43, 8.24) | 3.20 (2.25, 4.73) | 0.000 |
 Resistin (ng/mL) | 4.95 (3.85, 6.54) | 4.66 (3.68, 5.79) | 4.85 (3.87, 6.55) | 5.20 (3.99, 6.94) | 0.019 | 4.79 (3.71, 6.31) | 5.49 (4.39, 7.61) | 0.007 |
 PAI-1 (ng/mL) | 25.53 (18.68, 33.31) | 21.80 (16.13, 29.69) | 24.27 (18.60, 33.34) | 28.55 (19.98, 37.67) | 0.005 | 23.24 (17.35, 31.17) | 31.76 (24.49, 40.16) | 0.000 |
 WBC (109/L) | 5.60 (4.80, 6.70) | 5.30 (4.40, 6.40) | 5.50 (4.80, 6.50) | 6.00 (5.30, 7.50) | 0.011 | 4.60 (5.50, 6.50) | 6.30 (5.40, 7.50) | 0.000 |
Physical activity (mins per week) | ||||||||
 Sedentary | 909 (853, 971) | 894 (844, 970) | 905 (843, 951) | 945 (879, 991) | 0.003 | 898 (840, 957) | 952 (891, 994) | <0.0001 |
 Light | 103 (69, 135) | 107 (68, 134) | 108 (78, 138) | 91 (58, 127) | 0.04 | 109 (75, 141) | 85 (55, 119) | 0.0001 |
 MVPA | 62 (32, 103) | 70 (42, 110) | 67 (38, 104) | 45 (23, 80) | 0.0008 | 69 (38, 107) | 45 (22, 68) | 0.0001 |