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Table 1 Characteristics and inflammatory and physical activity profiles of the study sample and subgroups

From: Does replacing sedentary behaviour with light or moderate to vigorous physical activity modulate inflammatory status in adults?

  Entire sample Normal weight Overweight Obese P Non-insulin resistant Insulin resistant P
n 396 79 189 128   293 97  
Age (years) 59.58 ± 5.46 58.51 ± 5.43 59.73 ± 5.45 59.58 ± 5.43 0.13 59.49 ± 5.48 59.83 ± 5.44 0.61
Male (%) 46 64.6 54.5 46.9 0.046 41.7 56.7 0.01
BMI (kg/m2) 28.86 ± 4.55 23.25 ± 1.54 27.77 ± 1.35 33.95 ± 3.61 0.000 27.54 ± 3.61 32.85 ± 4.86 0.000
Waist (cm) 96.27 ± 13.39 82.80 ± 8.24 93.51 ± 0.00 108.70 ± 10.85 0.000 92.56 ± 12.04 107.29 ± 11.29 0.000
HOMA-IR 2.96 ± 3.25 1.49 ± 0.95 2.14 ± 1.50 5.11 ± 4.72 0.000 1.68 ± 0.80 6.87 ± 4.56 0.000
Inflammatory profiles
 C3 (mg/dL) 136.40 (120.30, 152.09) 115.68 (108.12, 138.27) 134.72 (121.63, 149.40) 147.60 (132.70, 166.90) 0.000 130.89 (115.87, 145.20) 152.52 (137.23,173.53) 0.000
 CRP (ng/mL) 1.35 (0.99, 2.36) 1.02 (0.78, 1.55) 1.34 (1.03, 2.21) 1.68 (1.10, 3.06) 0.000 1.29 (0.97, 1.90) 1.95 (1.16, 3.34) 0.000
 IL-6 (pg/mL) 1.78 (1.19, 2.97) 1.30 (0.90, 2.06)) 1.67 (1.13, 2.62) 2.42 (1.63, 3.76) 0.000 1.53 (1.09, 2.53) 2.54 (1.69, 3.78) 0.000
 TNF(pg/mL) 5.86 (4.73, 7.18) 5.67 (4.40, 7.10) 5.79 (4.67, 7.04) 6.05 (4.94, 7.82) 0.140 5.55 (4.59, 6.80) 6.89 (5.66, 8.65) 0.000
 Leptin (ng/mL) 2.03 (1.25, 3.16) 1.38 (0.75, 2.00) 2.00 (1.14, 2.75) 3.01 (1.90, 4.87) 0.000 1.89 (1.14, 2.74) 2.78 (1.55,4.92) 0.001
 ACDC (ng/mL) 4.86 (2.86, 7.54) 7.46 (3.89, 10.27) 5.03 (3.17, 7.65) 3.80 (2.45, 5.81) 0.000 5.48 (3.43, 8.24) 3.20 (2.25, 4.73) 0.000
 Resistin (ng/mL) 4.95 (3.85, 6.54) 4.66 (3.68, 5.79) 4.85 (3.87, 6.55) 5.20 (3.99, 6.94) 0.019 4.79 (3.71, 6.31) 5.49 (4.39, 7.61) 0.007
 PAI-1 (ng/mL) 25.53 (18.68, 33.31) 21.80 (16.13, 29.69) 24.27 (18.60, 33.34) 28.55 (19.98, 37.67) 0.005 23.24 (17.35, 31.17) 31.76 (24.49, 40.16) 0.000
 WBC (109/L) 5.60 (4.80, 6.70) 5.30 (4.40, 6.40) 5.50 (4.80, 6.50) 6.00 (5.30, 7.50) 0.011 4.60 (5.50, 6.50) 6.30 (5.40, 7.50) 0.000
Physical activity (mins per week)
 Sedentary 909 (853, 971) 894 (844, 970) 905 (843, 951) 945 (879, 991) 0.003 898 (840, 957) 952 (891, 994) <0.0001
 Light 103 (69, 135) 107 (68, 134) 108 (78, 138) 91 (58, 127) 0.04 109 (75, 141) 85 (55, 119) 0.0001
 MVPA 62 (32, 103) 70 (42, 110) 67 (38, 104) 45 (23, 80) 0.0008 69 (38, 107) 45 (22, 68) 0.0001
  1. Values are presented as mean ± S.D., %, and median (25th, 75th percentiles). ANOVA, t-tests and non-parametric tests were used to compare mean, % and median values, respectively, in subgroups according to BMI and HOMA-IR cut-offs. ACDC adiponectin, C3 Complement component C3, CRP C reactive protein, IL6 interleukin 6, PAI-1 plasminogen activator inhibitor-1, TNF-α tumour necrosis factor α, WBC White blood cell