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Table 1 Characteristics and inflammatory and physical activity profiles of the study sample and subgroups

From: Does replacing sedentary behaviour with light or moderate to vigorous physical activity modulate inflammatory status in adults?

 

Entire sample

Normal weight

Overweight

Obese

P

Non-insulin resistant

Insulin resistant

P

n

396

79

189

128

 

293

97

 

Age (years)

59.58 ± 5.46

58.51 ± 5.43

59.73 ± 5.45

59.58 ± 5.43

0.13

59.49 ± 5.48

59.83 ± 5.44

0.61

Male (%)

46

64.6

54.5

46.9

0.046

41.7

56.7

0.01

BMI (kg/m2)

28.86 ± 4.55

23.25 ± 1.54

27.77 ± 1.35

33.95 ± 3.61

0.000

27.54 ± 3.61

32.85 ± 4.86

0.000

Waist (cm)

96.27 ± 13.39

82.80 ± 8.24

93.51 ± 0.00

108.70 ± 10.85

0.000

92.56 ± 12.04

107.29 ± 11.29

0.000

HOMA-IR

2.96 ± 3.25

1.49 ± 0.95

2.14 ± 1.50

5.11 ± 4.72

0.000

1.68 ± 0.80

6.87 ± 4.56

0.000

Inflammatory profiles

 C3 (mg/dL)

136.40 (120.30, 152.09)

115.68 (108.12, 138.27)

134.72 (121.63, 149.40)

147.60 (132.70, 166.90)

0.000

130.89 (115.87, 145.20)

152.52 (137.23,173.53)

0.000

 CRP (ng/mL)

1.35 (0.99, 2.36)

1.02 (0.78, 1.55)

1.34 (1.03, 2.21)

1.68 (1.10, 3.06)

0.000

1.29 (0.97, 1.90)

1.95 (1.16, 3.34)

0.000

 IL-6 (pg/mL)

1.78 (1.19, 2.97)

1.30 (0.90, 2.06))

1.67 (1.13, 2.62)

2.42 (1.63, 3.76)

0.000

1.53 (1.09, 2.53)

2.54 (1.69, 3.78)

0.000

 TNF(pg/mL)

5.86 (4.73, 7.18)

5.67 (4.40, 7.10)

5.79 (4.67, 7.04)

6.05 (4.94, 7.82)

0.140

5.55 (4.59, 6.80)

6.89 (5.66, 8.65)

0.000

 Leptin (ng/mL)

2.03 (1.25, 3.16)

1.38 (0.75, 2.00)

2.00 (1.14, 2.75)

3.01 (1.90, 4.87)

0.000

1.89 (1.14, 2.74)

2.78 (1.55,4.92)

0.001

 ACDC (ng/mL)

4.86 (2.86, 7.54)

7.46 (3.89, 10.27)

5.03 (3.17, 7.65)

3.80 (2.45, 5.81)

0.000

5.48 (3.43, 8.24)

3.20 (2.25, 4.73)

0.000

 Resistin (ng/mL)

4.95 (3.85, 6.54)

4.66 (3.68, 5.79)

4.85 (3.87, 6.55)

5.20 (3.99, 6.94)

0.019

4.79 (3.71, 6.31)

5.49 (4.39, 7.61)

0.007

 PAI-1 (ng/mL)

25.53 (18.68, 33.31)

21.80 (16.13, 29.69)

24.27 (18.60, 33.34)

28.55 (19.98, 37.67)

0.005

23.24 (17.35, 31.17)

31.76 (24.49, 40.16)

0.000

 WBC (109/L)

5.60 (4.80, 6.70)

5.30 (4.40, 6.40)

5.50 (4.80, 6.50)

6.00 (5.30, 7.50)

0.011

4.60 (5.50, 6.50)

6.30 (5.40, 7.50)

0.000

Physical activity (mins per week)

 Sedentary

909 (853, 971)

894 (844, 970)

905 (843, 951)

945 (879, 991)

0.003

898 (840, 957)

952 (891, 994)

<0.0001

 Light

103 (69, 135)

107 (68, 134)

108 (78, 138)

91 (58, 127)

0.04

109 (75, 141)

85 (55, 119)

0.0001

 MVPA

62 (32, 103)

70 (42, 110)

67 (38, 104)

45 (23, 80)

0.0008

69 (38, 107)

45 (22, 68)

0.0001

  1. Values are presented as mean ± S.D., %, and median (25th, 75th percentiles). ANOVA, t-tests and non-parametric tests were used to compare mean, % and median values, respectively, in subgroups according to BMI and HOMA-IR cut-offs. ACDC adiponectin, C3 Complement component C3, CRP C reactive protein, IL6 interleukin 6, PAI-1 plasminogen activator inhibitor-1, TNF-α tumour necrosis factor α, WBC White blood cell