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Table 4 Crude and adjusteda odds ratios for pregnancy outcomes among women 20+ weeks of gestation according to leisure-time physical activity trajectory class across nuMoM2b study visits

From: Patterns of leisure-time physical activity across pregnancy and adverse pregnancy outcomes

Pregnancy outcome

Pregnancy outcome

Crude odds ratios

Adjusted odds ratios

 Physical activity trajectory

 Class (Contrast)b

n/N (%)

Estimate (95% CI)

p-value

Estimate (95% CI)

p-value

Preterm birth (Nc = 9465, Na = 9278)

 High (referent)

247/3272 (7.5)

1.00

0.0175

1.00

0.1998

 Early decreasing (versus referent)

90/980 (9.2)

1.24 (0.96–1.59)

1.12 (0.86–1.46)

 Early increasing (versus referent)

118/1300 (9.1)

1.22 (0.97–1.54)

1.09 (0.86–1.39)

 Late decreasing (versus referent)

194/2278 (8.5)

1.14 (0.94–1.39)

1.09 (0.89–1.33)

 Low (versus referent)

170/1635 (10.4)

1.42 (1.16–1.74)

1.31 (1.05–1.63)

Spontaneous preterm birth (Nc = 9461, Na = 9274)

 High (referent)

160/3271 (4.9)

1.00

0.4563

1.00

0.5995

 Early decreasing (versus referent)

54/978 (5.5)

1.14 (0.83–1.56)

1.09 (0.78–1.52)

 Early increasing (versus referent)

63/1300 (4.8)

0.99 (0.73–1.34)

0.95 (0.70–1.29)

 Late decreasing (versus referent)

105/2278 (4.6)

0.94 (0.73–1.21)

0.94 (0.72–1.21)

 Low (versus referent)

95/1634 (5.8)

1.20 (0.92–1.56)

1.17 (0.88–1.54)

Preeclampsia (Nc = 9450, Na = 9263)

 High (referent)

163/3270 (5.0)

1.00

0.0098

1.00

0.6210

 Early decreasing (versus referent)

64/976 (6.6)

1.34 (0.99–1.80)

1.05 (0.77–1.44)

 Early increasing (versus referent)

94/1299 (7.2)

1.49 (1.14–1.93)

1.21 (0.92–1.59)

 Late decreasing (versus referent)

149/2273 (6.6)

1.34 (1.06–1.68)

1.13 (0.89–1.43)

 Low (versus referent)

115/1632 (7.0)

1.44 (1.13–1.85)

1.18 (0.91–1.53)

Preeclampsia or antepartum gHTN (Nc = 9450, Na = 9263)

 High (referent)

372/3270 (11.4)

1.00

0.0066

1.00

0.3719

 Early decreasing (versus referent)

131/976 (13.4)

1.21 (0.98–1.49)

1.03 (0.82–1.29)

 Early increasing (versus referent)

186/1299 (14.3)

1.30 (1.08–1.57)

1.16 (0.95–1.41)

 Late decreasing (versus referent)

326/2273 (14.3)

1.30 (1.11–1.53)

1.14 (0.97–1.35)

 Low (versus referent)

227/1632 (13.9)

1.26 (1.05–1.50)

1.16 (0.96–1.40)

GDM (Nc = 9314, Na = 9131)

 High (referent)

101/3245 (3.1)

1.00

0.0003

1.00

0.0001

 Early decreasing (versus referent)

48/956 (5.0)

1.65 (1.16–2.34)

1.74 (1.21–2.52)

 Early increasing (versus referent)

48/1270 (3.8)

1.22 (0.86–1.73)

1.16 (0.81–1.68)

 Late decreasing (versus referent)

105/2226 (4.7)

1.54 (1.17–2.04)

1.50 (1.12–2.01)

 Low (versus referent)

92/1617 (5.7)

1.88 (1.41–2.51)

2.00 (1.47–2.73)

SGA < 5th percentile (Nc = 9426, Na = 9239)

 High (referent)

123/3260 (3.8)

1.00

0.1649

1.00

0.2169

 Early decreasing (versus referent)

45/974 (4.6)

1.24 (0.87–1.75)

1.13 (0.78–1.63)

 Early increasing (versus referent)

63/1294 (4.9)

1.31 (0.96–1.78)

1.15 (0.83–1.60)

 Late decreasing (versus referent)

116/2270 (5.1)

1.37 (1.06–1.78)

1.37 (1.05–1.79)

 Low (versus referent)

76/1628 (4.7)

1.25 (0.93–1.67)

1.08 (0.79–1.47)

  1. aAdjusted for age (linear and quadratic terms), race/ethnicity (white, non-Hispanic; black, non-Hispanic; Hispanic; Asian: and other), early pregnancy BMI (linear and quadratic terms), and smoking status 3 months prior to pregnancy. P-values are taken from logistic regression models
  2. bNc and Na present the number of observations used in calculating the crude odds ratios and the adjusted odds ratios, respectively