Long-term changes in body weight and physical activity in relation to all-cause and cardiovascular mortality: the HUNT study

Table 3 Combined effect of concurrent changes in weight and leisure-time physical activity on cardiovascular mortality

Change in leisure -time physical activity	Change in weight^a
	Loss (≥5%)			Stable (< 5% change)		Gain (≥5%)
	Person years/ death	Adjusted HR^b	95% CI	Person years/ death	Adjusted HR^b	95% CI	Person years/ death	Adjusted HR^b	95% CI
Cardiovascular Mortality
Remained active	25,127/483	1.56	1.40, 1.74	154,446/1102	1.00	Reference	279,598/802	1.06	0.96, 1.16
Inactive to active	2763/54	1.40	1.06, 1.84	11,934/126	1.32	1.10, 1.59	21,739/96	1.28	1.04, 1.58
Active to inactive	2850/123	1.70	1.41, 2.06	9558/191	1.60	1.36, 1.86	16,577/139	1.46	1.22, 1.75
Remained inactive	1145/44	2.25	1.66, 3.05	3656/58	1.37	1.05, 1.79	5960/146	1.57	1.17, 2.12

Abbreviations: CI confidence interval, HR hazard ratio
^aCalculated as change in kilograms between the baseline in HUNT1 and last examination in HUNT2
^bAdjusted for age, sex, education (< 10 years, 10 to 12 years, and ≥ 13 years, unknown), smoking status (never, former, current, unknown), alcohol consumption (0 units, 1–4 units, ≥5 units, unknown), insomnia symptoms (no, yes, unknown), and history of cardiovascular disease (no, yes, unknown)

ISSN: 1479-5868