Skip to main content

Table 2 Primary intention-to-treat analyses of primary and secondary outcomes at 6 months for participants providing data

From: The community-based prevention of diabetes (ComPoD) study: a randomised, waiting list controlled trial of a voluntary sector-led diabetes prevention programme

 Waiting list control groupIntervention groupBetween group difference*p-value
Baseline
n = 157
unless indicated
6-months
n = 144
unless indicated
Baseline
n = 157
unless indicated
6-months
n = 141
unless indicated
Mean (95% CI) or odds ratio (OR) (95% CI) where indicated 
Primary outcome 
 Weight loss (kg)n/a−0.10 (3.03)n/a−1.91 (4.49)−1.72 (−2.59 to − 0.85)<0.001
Secondary weight-related outcomes
 N (%) > 3% weight lossn/a23 (16)n/a46 (33)OR = 2.53 (1.41 to 4.52)0.002
 N (%) > 5% weight lossn/a12 (8)n/a29 (21)OR = 2.83 (1.36 to 5.90)0.006
 Mean (SD) BMI (kg/m2)31.56 (4.39)31.58 (4.60)31.85 (4.66)31.07 (4.53)−0.64 (−0.95 to − 0.33)<0.001
 Mean (SD) waist circumference (cm)104.80 (11.28)104.11 (11.48)104.85 (12.62)102.36 (12.50)−1.36 (−2.36 to −0.36)0.008
Other secondary objective outcomes
 Mean (SD) HbA1c (mmol/mol)39.69 (2.73)40.18a (3.22)39.88 (3.06)39.71 (5.70)−0.76 (−1.73 to 0.21)0.124
 Mean (SD) blood pressure systolic (mmHg)137.58 (18.82)138.44 (17.20)136.22 (17.10)136.91 (17.48)−0.51 (−3.69 to 2.67)0.752
 Mean (SD) blood pressure diastolic (mmHg)79.83 (10.60)79.85 (9.33)78.97 (10.37)78.21 (9.77)−0.81 (−2.62 to 1.01)0.383
 Mean (SD) total mins moderate-vigorous activity (MVPA) per week318.67b (176.07)312.95c (207.80)337.34d (189.12)332.05e (206.24)−11.22 (−48.21 to 25.78)0.551
 Mean (SD) total mins MVPA in 10+ min bouts per week73.55b (96.67)79.57c (127.99)80.09d (116.85)82.45e (130.36)−8.23 (−30.92 to 14.46)0.475
 N (%) meeting recommendation for 150 mins MVPA in 10+ min bouts per week22b (16)20c (19)25d (17)20e (18)OR = 0.72 (0.31 to 1.68)0.448
Secondary self-reported outcomes
 Dietary behaviour fat subscale scores (0 to 3, lower better)1.95f (0.39)1.92g (0.33)1.94 (0.30)1.81h (0.33)−0.11 (−0.18 to −0.05)0.001
 Dietary behaviour fibre subscale score (0 to 3, higher better)2.17f (0.40)2.19g (0.42)2.17 (0.38)2.30h (0.38)0.12 (0.05 to 0.20)0.001
 Mean (SD) health rating (0–100, higher better)75.09i (17.37)73.65j (18.49)72.78k (19.95)77.24h (16.66)4.48 (0.85 to 8.11)0.016
 Mean (SD) life satisfaction rating (0–10, higher better)7.43i (1.90)7.48j (1.96)7.65 (2.03)7.73h (1.74)0.14 (−0.18 to 0.46)0.385
 Mean (SD) mental well-being scores (0–35, higher better)24.88f (5.09)24.07h (5.02)24.82 (4.69)24.99h (3.89)0.04 (−0.21 to 0.28)0.761
  1. *Mean differences, ORs and CIs adjusted for baseline outcome value, site, gender, age and baseline BMI category
  2. an = 142, 2 participants missing HbA1c due to machine malfunction;
  3. bn = 135, cn = 104, dn = 143, en = 112, with 4+ valid days, including a weekend day, of accelerometry data
  4. fn = 154; gn = 141; hn = 140; in = 152; jn = 139; kn = 156