| Outcome | Inactive time with time in bed | p-value | Inactive time with LPA | p-value | Inactive time with MVPA | p-value |
|---|
| Anthropometric measures |
| BMI (kg/m2) | −0.12 (−0.18;-0.05) | < 0.001 | −0.19 (− 0.27;-0.11) | < 0.001 | − 0.40 (− 0.55;-0.25) | < 0.001 |
| Waist circumference (cm) | − 0.29 (− 0.46;-0.13) | 0.001 | −0.42 (− 0.62;-0.21) | < 0.001 | −1.11 (−1.49;-0.72) | < 0.001 |
| Body composition |
| Total body fat (%) | −0.07 (− 0.21;0.08) | 0.391 | −0.43 (− 0.62;-0.25) | < 0.001 | −0.69 (− 1.03;-0.34) | < 0.001 |
| VAT (Kg) | − 0.03 (− 0.05;0.00) | 0.052 | −0.06 (− 0.09;-0.03) | 0.001 | −0.06 (− 0.12;0.01) | 0.075 |
| Total body muscle mass (%) | 0.05 (−0.09;0.20) | 0.465 | 0.40 (0.22;0.56) | < 0.001 | 0.62 (0.29;0.95) | < 0.001 |
| Clinical parameters |
| HbA1c (%) | −0.02 (− 0.04;-0.01) | 0.006 | − 0.03 (− 0.05;-0.01) | 0.002 | −0.08 (− 0.12;-0.05) | < 0.001 |
| Glucose (mg/dL) | − 0.09 (− 0.64;0.45) | 0.736 | −1.05 (− 1.73;-0.38) | 0.002 | −2.15 (−3.44;-0.87) | 0.001 |
| HDL (mg/dL) | 0.11 (− 0.10;0.31) | 0.306 | 0.27 (0.01;0.52) | 0.039 | 1.15 (0.67;1.63) | < 0.001 |
| LDL (mg/dL) | 0.30 (−0.58;1.19) | 0.502 | 0.34 (−0.75;1.43) | 0.538 | 1.43 (−0.63;3.48) | 0.174 |
| Triglycerides (mg/dL) | −0.89 (−2.35;0.58) | 0.235 | −1.98 (−3.78;-0.17) | 0.032 | −9.40 (−12.8;-5.99) | < 0.001 |
| SBP (mmHg) | 0.09 (−0.24;0.41) | 0.597 | −0.02 (− 0.42;0.38) | 0.906 | 0.35 (− 0.41;1.11) | 0.363 |
| DBP (mmHg) | −0.07 (− 0.26;0.11) | 0.431 | − 0.08 (− 0.30;0.15) | 0.505 | 0.36 (− 0.07;0.79) | 0.105 |
- Values shown are β (95% CI). These represent the change in outcome variables when substituting 30 min/day of inactive time with time in bed and physical activity. Abbreviations: LPA light physical activity, MVPA moderate-vigorous physical activity, BMI body mass index, VAT visceral adipose tissue, HbA1c glycated haemoglobin, HDL high density lipoprotein, LDL low-density lipoprotein, SBP; systolic blood pressure, DBP diastolic blood pressure. Linear regression models were used to assess isotemporal substitution of inactive time with: time in bed, light PA and MVPA, adjusting for age, sex, educational level, marital status, erMedDiet, smoking and total wear time
- aT1, Men (min 3.79 / max 7.6), Women (min 2.64 / max 7.15). T2 Men (min 7.61 / 9.34max); Women (min 7.16 / 8.73max). T3, Men (min 9.35 / 17.2 max), Women (min 8.74/ 15.15max). Tertiles were calculated using the total sample of 2189, and the sample size shown corresponds to the distribution of these 2189 individuals within tertiles
