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Table 2 Cardiac death outcomes and multivariate cox regression analyses

From: Dose-response association of implantable device-measured physical activity with long-term cardiac death and all-cause mortality in patients at high risk of sudden cardiac death: a cohort study

  No. of events No. of participants Model 1 Model 2 Model 3 P trend
Tertile 1 51 274 Ref. Ref. Ref. < 0.001
Tertile 2 24 274 0.40 (0.25–0.66) 0.42 (0.26–0.69) 0.41 (0.25–0.68)
Tertile 3 15 274 0.25 (0.14–0.45) 0.26 (0.14–0.48) 0.28 (0.15–0.51)
Age, years
  < 60
  Tertile 1 10 76 Ref. Ref. Ref. 0.127
  Tertile 2 11 121 0.57 (0.24–1.35) 0.76 (0.31–1.85) 0.82 (0.33–2.04)
  Tertile 3 8 163 0.29 (0.11–0.74) 0.39 (0.15–1.06) 0.47 (0.17–1.26)
  ≥ 60
  Tertile 1 41 198 Ref. Ref. Ref. < 0.001
  Tertile 2 13 153 0.35 (0.19–0.65) 0.34 (0.18–0.65) 0.34 (0.18–0.64)
  Tertile 3 7 111 0.25 (0.11–0.57) 0.24 (0.11–0.55) 0.25 (0.11–0.57)
  1. Model 1 adjusted for age and gender; Model 2 further adjusted for Model 1 puls primary prevention, NYHA, CRT-D, LVEF, LVEDD, β-blockers, and aldosterone antagonists; Model 3 adjusted factors in Model 2 and potential mediators on the causal pathway including BMI, ischemic cardiomyopathy, hypertension, AF, diabetes, prior myocardial infarction