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Table 3 All-cause mortality outcomes and multivariate cox regression analyses

From: Dose-response association of implantable device-measured physical activity with long-term cardiac death and all-cause mortality in patients at high risk of sudden cardiac death: a cohort study

  No. of events No. of participants Model 1 Model 2 Model 3 P trend
Tertile 1 108 274 Ref. Ref. Ref. < 0.001
Tertile 2 56 274 0.46 (0.33–0.64) 0.47 (0.34–0.66) 0.46 (0.33–0.64)
Tertile 3 27 274 0.23 (0.15–0.35) 0.24 (0.15–0.37) 0.24 (0.16–0.38)
Age, years
  < 60
  Tertile 1 26 76 Ref. Ref. Ref. < 0.001
  Tertile 2 20 121 0.40 (0.22–0.72) 0.55 (0.30–1.01) 0.55 (0.30–1.01)
  Tertile 3 14 163 0.21 (0.11–0.40) 0.28 (0.14–0.56) 0.29 (0.15–0.59)  
  ≥ 60
  Tertile 1 82 198 Ref. Ref. Ref. < 0.001
  Tertile 2 36 153 0.49 (0.33–0.73) 0.47 (0.31–0.70) 0.46 (0.31–0.70)
  Tertile 3 13 111 0.24 (0.13–0.44) 0.23 (0.12–0.41) 0.23 (0.13–0.43)
  1. Model 1 adjusted for age and gender; Model 2 further adjusted for Model 1 puls primary prevention, NYHA, CRT-D, LVEF, LVEDD, β-blockers, and aldosterone antagonists; Model 3 adjusted factors in Model 2 and potential mediators on the causal pathway including BMI, ischemic cardiomyopathy, hypertension, AF, diabetes, prior myocardial infarction