Table 3 Association between extended ICH score at age 5–6 years and cardiovascular health outcomes at age 11–12 years
From: Ideal cardiovascular health at age 5–6 years and cardiometabolic outcomes in preadolescence
| Ideal Cardiovascular Health Scorea | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| All | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | P for trend | |
| N, % | 559 | 2 (0.4) | 4 (0.7) | 6 (1.1) | 38 (6.8) | 119 (21.3) | 198 (35.4) | 187 (33.5) | 5 (0.9) | |
| Age at first measurement (years), mean (SD) | 5.7 (0.4) | 5.5 (0.2) | 5.7 (0.4) | 5.7 (0.5) | 5.8 (0.5) | 5.7 (0.4) | 5.7 (0.5) | 5.7 (0.4) | 5.6 (0.5) | 0.943 |
| Age at follow up (years), mean (SD) | 11.8 (0.4) | 12.1 (0.3) | 11.4 (0.2) | 12.0 (0.4) | 11.9 (0.3) | 11.7 (0.4) | 11.8 (0.4) | 11.8 (0.3) | 11.5 (0.3) | 0.011 |
| Maturation, mean (SD) | 1.5 (0.5) | 1.5 (0.1) | 2.1 (1.1) | 1.7 (0.8) | 1.6 (0.5) | 1.5 (0.6) | 1.5 (0.6) | 1.4 (0.4) | 1.3 (0.5) | 0.107 |
| Cardiovascular health 11/12y | ||||||||||
| Glucose (mmol/L), mean (SE) | 4.9 (0.0) | 4.5 (0.4) | 4.6 (0.3) | 4.8 (0.2) | 5.2 (0.1) | 4.9 (0.1) | 4.9 (0.0) | 4.9 (0.0) | 4.6 (0.3) | 0.920 |
| Total cholesterol (mmol/L), mean (SE) | 4.1 (0.0) | 5.0 (0.4) | 4.5 (0.3) | 4.1 (0.3) | 4.1 (0.1) | 4.3 (0.1) | 4.1 (0.0) | 3.9 (0.0) | 3.5 (0.3) | < 0.001 |
| Systolic BP (mmHg), mean (SE) | 105.2 (0.4) | 110.8 (5.8) | 110.6 (4.1) | 113.0 (3.7) | 106.8 (1.4) | 105.2 (0.8) | 105.1 (0.6) | 104.2 (0.6) | 109.3 (3.7) | 0.012 |
| Diastolic BP (mmHg), mean (SE) | 60.1 (0.3) | 64.4 (4.6) | 63.2 (3.2) | 68.9 (2.9) | 60.6 (1.1) | 60.5 (0.6) | 60.1 (0.5) | 59.1 (0.5) | 66.5 (2.9) | 0.011 |
| HDL-C (mmol/L), mean (SE) | 1.5 (0.0) | 1.4 (0.2) | 1.5 (0.2) | 1.4 (0.1) | 1.5 (0.1) | 1.5 (0.0) | 1.5 (0.0) | 1.5 (0.0) | 1.0 (0.2) | 0.309 |
| Triglyceriden (mmol/L), mean (SE) | 1.0 (0.0) | 1.0 (0.4) | 0.8 (0.3) | 1.2 (0.2) | 1.1 (0.1) | 1.0 (0.1) | 0.9 (0.0) | 1.0 (0.0) | 0.5 (0.4) | 0.468 |
| BMI, mean (SE) | 17.6 (0.1) | 20.3 (1.6) | 20.2 (1.1) | 22.1 (1.0) | 18.2 (0.4) | 18.4 (0.2) | 17.2 (0.2) | 17.2 (0.2) | 17.1 (1.0) | < 0.001 |
| CIMT (mm), mean (SE) | 0.462 (0.001) | 0.445 (0.020) | 0.485 (0.015) | 0.429 (0.020) | 0.455 (0.006) | 0.458 (0.003) | 0.462 (0.002) | 0.464 (0.002) | 0.457 (0.013) | 0.123 |