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Table 6 Difference in cost and effects (change in two or three behaviours and cardiovascular risk); ICER between intervention and control patients and Relative Value Index (RVI) for the main and sensitivity analyses based on adjusted models

From: Cost-effectiveness analysis of a multiple health behaviour change intervention in people aged between 45 and 75 years: a cluster randomized controlled trial in primary care (EIRA study)

 

Usual Care Cost (95% CI) in €

Usual Care % Change in two or three behaviours in one patient (95% CI)d

ICER (€/extra change in two or three behaviours in one patient)

RVI

Usual care REGICOR (95% CI)

ICER (€/REGICOR reduction)

RVI

Main analysis - Societal perspective (ITT and minimum wage)

295.02 (− 1402.75; 1992.78)

5.27 (2.59; 7.78)

5598

5598

0.04 (− 0.12; 0.21)

6926

6926

Main analysis – Healthcare system perspective (ITT and minimum wage)

207.20 (− 1901.24; 2315.63)

5.27 (2.59; 7.78)

3932

3932

0.04 (− 0.12; 0.21)

4864

4864

Mean wage (Societal perspective)

433.19 (− 1487.19; 2354.10)

5.27 (2.59; 7.78)

8220

8220

0.04 (− 0.12; 0.21)

10,169

10,169

Maximum regional tariffsa

266.19 (−2405.15 2507.52)

5.27 (2.59; 7.78)

5051

5051

0.04 (− 0.12; 0.21)

6285

6285

Minimum regional tariffs

271,64 (− 1137.75; 1681.02)

5.27 (2.59; 7.78)

6377

6377

0.04 (− 0.12; 0.21)

5154

5154

Complete-case

126.76 (−1.535.45; 1788.98)

5.68 (3.41;7.99)

2224

2224

0.06 (− 0.10; 0.21)

2174

2174

Unadjusted analysisb

343.60 (−1406.84; 2094.05)

4.47 (2.82; 8.09)

7690

7690

0.05 (− 0.12; 0.21)

7288

7288

SUR

129.82 (− 16.79; 276.43)c

NA

NA

NA

0.04 (− 0.002; 0.087)

3048

3048

  1. All sensitivity analyses considered societal perspective. SUR: Seemingly unrelated regressions. Bold letters refer to statistically significant differences between groups. a Minimum daily wage is maintained as unit cost for sick leave in this sensitivity analysis. b Only adjusted by baseline costs or effects. cConfidence interval in cost when CVR is consider as effect is (− 16.21; 275.85). dConfidence interval calculated based on bootstrapping. NA: Not applicable due to the outcome not being a continuous variable