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Table 2 Predictive values of PA for long-term mortality

From: Association between cardiac autonomic function and physical activity in patients at high risk of sudden cardiac death: a cohort study

  Univariable Cox regression model Multivariable Cox regression model 1 Multivariable Cox regression model 2
  HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
Primary endpoint: cardiac death
 Per 1%/increasea 0.904 (0.858–0.952) P < 0.001 0.887 (0.834–0.944) P < 0.001 0.897 (0.844–0.954) P = 0.001
 ≥11.0% group vs < 11.0% group 0.280 (0.154–0.509) P < 0.001 0.239 (0.124–0.460) P < 0.001 0.273 (0.142–0.526) P < 0.001
Secondary endpoint: all-cause mortality
 Per 1%/increasea 0.886 (0.848–0.926) P < 0.001 0.880 (0.836–0.926) P < 0.001 0.888 (0.844–0.933) P < 0.001
 ≥11.0% group vs < 11.0% group 0.276 (0.170–0.449) P < 0.001 0.277 (0.163–0.469) P < 0.001 0.299 (0.177–0.505) P < 0.001
  1. Multivariable Cox regression model 1 was adjusted for age at implantation, sex, BMI, LVEF, LVEDD, ICD or CRT-D implantation, NYHA Class, hypertension, DM, stroke, DCM, ICM, MI, PCI, pre-implant syncope, prior AF, use of ACEIs/ARBs, use of diuretics, and use of aldosterone antagonists. Multivariate Cox regression model 2 was adjusted for the above-mentioned confounders and additional HRV
  2. ACEIs/ARBs angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, AF atrial fibrillation, BMI body mass index, CI confidence interval, CRT-D cardiac resynchronisation therapy defibrillator, DM diabetic mellitus, HRV heart rate variability, HR hazard ratio, ICD implantable cardioverter defibrillator, ICM ischaemic cardiomyopathy, LVEF left ventricular ejection fraction, LVEDD left ventricular end-diastolic dimension, MI myocardial infarction, NYHA New York Heart Association, PA physical activity, PCI percutaneous coronary intervention
  3. a each additional 1% increase in PA