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Table 2 Unadjusted change in health measures at 6 months and completion

From: ‘Finishing the race’ – a cohort study of weight and blood glucose change among the first 36,000 patients in a large-scale diabetes prevention programme

 

Retained to 6 m

(n = 36,607)

Completed

(n = 22,697)

IA to 6 m

IA to completion

Change in HbA1c (mmol/mol)a

 n

20,682

15,017

 mean (SD)

−1.7 (4.3)

− 2.3 (4.3)

Change in HbA1c (%)

 n

20,682

15,017

 mean (SD)

−0.16 (0.39)

−0.21 (0.39)

Change in HbA1c categoryb

Normal at IA

  Normal at follow up

8896 (85.4)

6324 (87.4)

  NDH at follow up

1456 (14.0)

859 (11.9)

  T2D at follow up

63 (0.6)

49 (0.7)

NDH at IA

  Normal at follow up

5782 (60.1)

5002 (68.2)

  NDH at follow up

3575 (37.2)

2196 (29.9)

  T2D at follow up

257 (2.7)

142 (1.9)

T2D at IA

  Normal at follow up

265 (39.5)

233 (51.3)

  NDH at follow up

260 (38.8)

165 (36.3)

  T2D at follow up

146 (21.8)

56 (12.3)

Change in weight (kg)c

 n

24,949

19,794

 mean (SD)

−3.2 (4.4)

−3.6 (4.8)

Percentage change in weight

 n

24,949

19,794

 mean (SD)

−3.8 (5.0)

−4.2 (5.5)

Change in BMI (kg/m2)

 n

24,801

19,667

 mean (SD)

−1.2 (1.6)

−1.3 (1.7)

  1. Abbreviations: IA initial assessment, NDH non-diabetic hyperglycaemia, T2D type 2 diabetes
  2. a These are descriptive summaries of those with a measure recorded at both initial assessment and the follow-up point. Many participants were not due to have HbA1c measured at initial assessment if their referral measure was less than 3 months old. All retained patients were included in the adjusted analysis after multiple imputation of missing initial assessment values
  3. b ‘Normal’ range: HbA1c < 42 mmol/mol or FPG < 5.5 mmol/l; ‘NDH’ range: HbA1c 42-47 mmol/mol or FPG 5.5–6.9 mmol/l inclusive; ‘T2DM’ range: HbA1c > 47 mmol/mol or FPG > 6.9 mmol/l
  4. c Six-month [final] weight is missing where no dated weight was recorded within 31 days of the six-month [final] HbA1c measure, or where no date is recorded for a six-month [final] HbA1c measure [and where no final-session weight was recorded]