Level of evidence | Explanation |
---|---|
Strong | Consistent findingsa in two or more RCTs of high quality (MMAT score 4 or 5). |
Moderate | Consistent findings in one high-quality RCT and one or more RCTs of low quality (MMAT score 0–3), or one high-quality RCT and one or more high-quality non-randomized studies. |
Limited | Consistent findings in one high-quality RCT, or two or more high-quality non-randomized studies, or one or more high-quality non-randomized studies, and one or more low-quality RCTs. |
Conflicting | contradictory findings, with less than 75% of the studies reporting consistent findings. |
Insufficient | The above criteria were not met. |