Physical activity from young adulthood to middle age and premature cardiovascular disease events: a 30-year population-based cohort study

Table 3 Associations between meeting the Department of Health and Human Services physical activity guidelines at age 18 and through the follow-up period and onset of cardiovascular disease events in the CARDIA study

	Any CHD			Any CHF			Any Stroke			Any CVD
	OR	95% CI	p	OR	95% CI	P	OR	95% CI	p	OR	95% CI	p
Expected total physical activity at age 18^a
< 300 EU	reference			reference			reference			reference
300–600 EU	0.50	0.34, 0.72	< 0.001	1.08	0.64, 1.82	0.770	0.69	0.42, 1.15	0.150	0.69	0.52, 0.91	0.010
> 600 EU	0.59	0.38, 0.93	0.024	0.60	0.27, 1.32	0.200	0.51	0.23,1.14	0.100	0.60	0.41, 0.88	0.008
Always meeting total physical activity level from young adulthood to middle age^a
< 300 EU	reference			reference			reference			reference
> 300 EU	0.60	0.42, 0.85	0.004	0.82	0.51, 1.32	0.420	0.74	0.46, 1.18	0.210	0.74	0.57, 0.96	0.021
> 600 EU	0.68	0.39, 1.19	0.180	0.23	0.05, 0.99	0.048	0.45	0.15, 1.36	0.160	0.55	0.34, 0.91	0.019

A total physical activity score of 300 exercise units (EU) approximates the Health and Human Services recommendations of approximately 150 minutes of moderate-intensity activity per week. Always meeting total physical activity level from young adulthood to middle age indicates that the estimated physical activity level from the linear mixed model was always above the threshold over the 30-year follow-up period
^aCovariates: age, race, sex, education, income, family history of cardiovascular disease, smoking status, and alcohol

ISSN: 1479-5868