https://ijbnpa.biomedcentral.com/articles/10.1186/1479-5868-5-46
https://ijbnpa.biomedcentral.com/articles/10.1186/1479-5868-5-45
https://ijbnpa.biomedcentral.com/articles/10.1186/1479-5868-5-44
https://ijbnpa.biomedcentral.com/articles/10.1186/1479-5868-5-47