Embedding weight management into safety-net pediatric primary care: randomized controlled trial

Table 2 Cardiometabolic Risk Parameters at Baseline and 12 Months by Randomization Group

Cardiometabolic Risk Parameters	Standard-of-Care Alone (n = 182)			Standard-of-Care + Enhanced Program (n = 178)			Difference in mean slope /12 months^a	Difference in mean slope^a	Overall group difference^a
Cardiometabolic Risk Parameters	Baseline	12 Months	p-value^b	Baseline	12 Months	p-value^b	Experimental - Control ±SE	p-value	p-value
Systolic blood pressure, mean (SD), mmHg	106.6 (10.2)	107.1 (12.9)	0.37	106.7 (11.1)	107.9 (12.3)	0.13	0.59 ± 1.36	0.67	0.87
Diastolic blood pressure, mean (SD), mmHg	58.7 (5.5)	58.8 (5.9)	0.94	58.1 (5.7)	58.0 (5.6)	0.87	−0.05 ± 0.74	0.94	0.38
Fasting Glucose, mean (SD), mmol/L	4.7 (0. 6)	4.8 (0.4)	0.19	4.7 (0.5)	4.8 (0.4)	0.13	−0.02 ± 0.06	0.70	0.65
2 Hour Glucose, mean (SD), mmol/L	5.4 (1.0)	5.66 (1.1)	0.11	5.4 (1.0)	5.4 (1.0)	0.74	−0.14 ± 0.13	0.25	0.18
Total Cholesterol, mean (SD), mmol/L	4.09 (0.77)	4.15 (0.75)	0.60	3.98 (0.69)	3.87 (0.69)	0.19	−0.1 ± 0.06	0.10	0.05
HDL Cholesterol, mean (SD), mmol/L	1.19 (0.24)	1.24 (0.27)	0.28	1.19 (0.26)	1.23 (0.30)	0.02	0.01 ± 0.02	0.48	0.67
LDL Cholesterol, mean (SD), mmol/L	2.46 (0.59)	2.41 (0.61)	0.07	2.35 (0.60)	2.18 (0.56)	0.01	−07 ± 0.05	0.11	0.04
Triglycerides, mean (SD), mmol/L	1.02 (0.71)	1.11 (0.61)	0.01	0.94 (0.49)	1.01 (0.56)	0.09	−0.06 ± 0.06	0.34	0.08
AST, mean (SD), ukat/L	0.50 (0.12)	0.45 (0.23)	0.01 ^c	0.53 (0.19)	0.40 (0.19)	0.01^c	−0.08 ± 0.03	0.01	0.02
ALT, mean (SD), ukat/L	0.41 (0.19)	0.45 (0.23)	0.15	0.45 (0.37)	0.40 (0.19)	0.01 ^c	−0.08 ± 0.03	0.01	0.03

^aBased on covariance pattern model and adjusted for child’s age, sex and ethnicity
^bPaired t-test
^cWilcoxon sign rank test
HDL, High-density lipoprotein, LDL, Low-density lipoprotein, ALT, alanine transaminase, AST, aspartate aminotransferase

ISSN: 1479-5868