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Table 2 Cost-effectiveness analysis results (main analysis – Societal perspective)

From: Cost-effectiveness of healthy eating and/or physical activity promotion in pregnant women at increased risk of gestational diabetes mellitus: economic evaluation alongside the DALI study, a European multicenter randomized controlled trial

HE + PA
Outcome measure Sample size ∆C (95%CI) ∆E (95%CI) ICER Distribution CE-plane (%)
  Intervention Control Points €/point NE SE SW NW
Gestational weight gain 107 104 380 (−811 to 1510) −2.3 (−3.7 to −0.9) −165 73.6 26.4 0.0 0.0
Fasting glucose 107 104 380 (−811 to 1510) 0.0 (−0.2 to 0.1) −9198 52.9 20.2 6.3 20.7
HOMA-IR 107 104 380 (−811 to 1510) 0.0 (−0.1 to 0.2) 8971 47.4 16.2 10.1 26.2
QALYs 107 104 −1627 (−4000 to 556) 0.02 (0.00 to 0.04) −91,254 7.8 88.8 3.0 0.4
HE
Outcome measure Sample size ∆C (95%CI) ∆E (95%CI) ICER Distribution CE-plane (%)
  Intervention Control Points €/point NE SE SW NW
Gestational weight gain 114 104 648 (−482 to 1759) −0.6 (−2.4 to 1.2) −1058 66.1 9.8 3.5 20.5
Fasting glucose 114 104 648 (−482 to 1759) 0.1 (0.0 to 0.3) 5247 2.7 0.7 12.6 83.9
HOMA-IR 114 104 648 (−482 to 1759) 0.2 (0.0 to 0.3) 4302 80.5 12.2 1.2 6.2
QALYs 114 104 653 (−1997 to 3343) 0.00 (−0.02 to 0.02) −241,959 24.9 12.9 18.7 43.6
PA
Outcome measure Sample size ∆C (95%CI) ∆E (95%CI) ICER Distribution CE-plane (%)
  Intervention Control Points €/point NE SE SW NW
Gestational weight gain 110 104 710 (−486 to 1875) 0.2 (−1.4 to 1.7) 4810 34.4 7.6 7.1 50.9
Fasting glucose 110 104 710 (−486 to 1875) 0.0 (−0.1 to 0.1) −74,480 48.8 8.9 5.8 36.6
HOMA-IR 110 104 710 (−486 to 1875) 0.1 (−0.1 to 0.3) 11,292 61.7 10.6 4.1 22.7
QALYs 110 104 −1155 (−3473 to 1142) 0.00 (−0.03 to 0.01) 146,179 2.9 16.3 65.9 14.8
  1. Abbreviations: C Costs, E Effects, ICER Incremental Cost-Effectiveness Ratio, CE-plane Cost-Effectiveness plane, NE Northeast-Quadrant, SE Southeast-Quadrant, NW Northwest-Quadrant, ZW Southwest-Quadrant