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Table 2 Associations of total inactive time with adiposity indicators and cardio-metabolic risk factors

From: Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study

 Tertiles of inactive time (h/day)ap for trendContinuous (per 30 min/d of inactive time)p-value
OutcomeT1 n = 735T2 n = 729T3 n = 725   
Anthropometric measures
 BMI (kg/m2)0 (ref.)0.22 (−0.14;0.58)0.90 (0.52;1.29)< 0.0010.11 (0.06;0.15)< 0.001
 Waist circumference (cm)0 (ref.)−0.05 (− 0.99;0.89)1.97 (0.96;2.97)< 0.0010.26 (0.15;0.37)< 0.001
Body Composition
 Total body fat (%)0 (ref.)0.69 (−0.14;1.53)1.41 (0.50;2.32)0.0020.17 (0.07;0.27)0.001
 VAT (Kg)0 (ref.)0.16 (0.00;0.31)0.23 (0.06;0.39)0.0130.03 (0.01;0.05)0.002
 Total body muscle mass (%)0 (ref.)−0.66 (−1.46;0.14)−1.30 (−2.17;-0.44)0.003− 0.16 (− 0.25;-0.06)0.002
Clinical Parameters
 HbA1c (%)0 (ref.)0.01 (−0.09;0.10)0.11 (0.01;0.21)0.0320.02 (0.01;0.03)< 0.001
 Glucose (mg/dL)0 (ref.)0.08 (−3.06;3.22)2.68 (−0.68;6.05)0.1160.47 (0.11;0.83)0.010
 HDL (mg/dL)0 (ref.)−1.02 (−2.19;0.15)− 1.64 (− 2.89;-0.39)0.010−0.20 (− 0.34;-0.07)0.003
 LDL (mg/dL)0 (ref.)1.16 (−3.87;6.19)− 1.23 (−6.63;4.17)0.652−0.19 (− 0.76;0.39)0.526
 Triglycerides (mg/dL)0 (ref.)8.58 (0.25;16.9)20.0 (11.0;28.9)< 0.0012.15 (1.20;3.11)< 0.001
 SBP (mmHg)0 (ref.)1.43 (−0.41;3.27)0.34 (−1.63;2.32)0.740−0.00 (− 0.21;0.21)0.981
 DBP (mmHg)0 (ref.)0.02 (−1.03;1.06)0.74 (−0.38;1.86)0.1950.14 (0.02;0.26)0.022
  1. Values shown are β (95% CI). Abbreviations: BMI body mass index, VAT visceral adipose tissue, HbA1c glycated haemoglobin, HDL high density lipoprotein, LDL low density lipoprotein, SBP systolic blood pressure, DBP; diastolic blood pressure. Linear regression models were used to assess the association between inactive time and each cardiometabolic risk outcomes, adjusting for age, sex, education level, marital status, erMedDiet, moderate-vigorous physical activity and smoking. a T1, Men (min 3.79 / max 7.6), Women (min 2.64 / max 7.15). T2 Men (min 7.61 / 9.34max); Women (min 7.16 / 8.73max). T3, Men (min 9.35 / 17.2 max), Women (min 8.74/ 15.15max). Tertiles were calculated using the total sample of 2189, and the sample size shown corresponds to the distribution of these 2189 individuals within tertiles; the sample size within tertiles varied for outcome variables with different total sample size. Sample sizes in tertiles of body composition variables determined by DXA were: T1, n = 225; T2, n = 219; T3, n = 218