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Table 3 Association of yearly changes in global dietary scores (GDSs) with concurrent changes in body weight or waist circumference over 5-year of follow-up by subgroups

From: Longitudinal association of changes in diet with changes in body weight and waist circumference in subjects at high cardiovascular risk: the PREDIMED trial

n = 7009

Body weight change (kg)

Waist circumference change (cm)

β (95% CI)

p-value

β (95% CI)

p-value

GDS (per 1 SD)

−0.16 (− 0.21, − 0.12)

< 0.0001

−0.27 (− 0.35, − 0.20)

< 0.0001

Sex

 Men (n = 2986)

− 0.14 (− 0.21, − 0.07)

< 0.0001

−0.18 (− 0.28, − 0.09)

< 0.0001

 Women (4023)

−0.18 (− 0.25, − 0.12)

< 0.0001

−0.35 (− 0.46, − 0.23)

< 0.0001

 p for interaction

 

0.498

 

0.019

Age

  < 65 (n = 2688)

−0.19 (− 0.26, − 0.11)

< 0.0001

−0.24 (− 0.36, − 0.13)

< 0.0001

  ≥ 65 (n = 4321)

−0.15 (− 0.21, − 0.09)

< 0.0001

−0.29 (− 0.39, − 0.19)

< 0.0001

 p for interaction

 

0.371

 

0.591

Obesity status

 Non-obese (n = 3723)

−0.15 (− 0.21, − 0.09)

< 0.0001

−0.21 (− 0.32, − 0.11)

< 0.0001

 Obese (n = 3286)

−0.19 (− 0.26, − 0.11)

< 0.0001

−0.35 (− 0.47, − 0.24)

< 0.0001

 p for interaction

 

0.445

 

0.076

Abdominal obesity status

 Non-abdominal obese (n = 1881)

−0.10 (− 0.18, − 0.02)

0.016

−0.18 (− 0.31, − 0.05)

0.007

 Abdominal obese (n = 5128)

−0.19 (− 0.25, − 0.13)

< 0.0001

−0.31 (− 0.41, − 0.22)

< 0.0001

 p for interaction

 

0.107

 

0.042

Diabetes status

 Non-diabetics (n = 3618)

−0.25 (− 0.32, − 0.18)

< 0.0001

−0.27 (− 0.38, − 0.17)

< 0.0001

 Diabetics (n = 3391)

−0.07 (− 0.13, 0.00)

0.037

−0.27 (− 0.38, − 0.16)

< 0.0001

 p for interaction

 

0.0001

 

0.864

Intervention group

 Controls (n = 2298)

−0.19 (− 0.27, − 0.11)

< 0.0001

−0.33 (− 0.48, − 0.18)

< 0.0001

 Intervention (n = 4711)

−0.15 (− 0.21, − 0.10)

< 0.0001

−0.25 (− 0.34, − 0.17)

< 0.0001

 p for interaction

 

0.317

 

0.503

  1. β (95% CI) represents difference in yearly change in body weight (kg) or waist circumference (cm) associated with increments of each GDS (per 1 SD). Model used for generalized estimating equation analysis was adjusted for time, sex, center, intervention group, age, baseline BMI/WC (depending on the outcome) and educational level, as well as yearly measured changes in smoking status and physical activity. Obesity was defined as BMI ≥30 kg/m2, and abdominal obesity as waist circumference ≥ 88 cm (women) and ≥ 102 cm (men)