|
Outcome
|
A (SE)
|
B (SE)
|
Direct (SE)
|
C (SE)
|
AB (SE)[95%CI]
|
|---|
|
Depressive Symptoms
|
2.99 (0.80)a
|
−0.10 (0.03)a
|
−0.25 (0.35)
|
− 0.56 (0.35)
|
−0.31 (0.12) [− 0.60,-0.11]
|
|
Anxiety Symptoms
|
3.01 (0.80)a
|
−0.04 (0.02)a
|
− 0.21 (0.22)
|
−0.32 (0.22)
|
− 0.11 (0.07) [− 0.27,-0.01]
|
|
Stress Symptoms
|
2.97 (0.80)a
|
− 0.12 (0.02)a
|
−0.26 (0.30)
|
− 0.63 (0.31)a
|
−0.37 (0.12) [− 0.65,-0.17]
|
|
QOL Physical Score
|
3.00 (0.80)a
|
0.02 (0.03)
|
0.28 (0.44)
|
0.36 (0.43)
|
0.07 (0.09) [−0.08,0.29]
|
|
QOL Mental Score
|
3.02 (0.80)a
|
0.17 (0.04)a
|
0.56 (0.57)
|
1.09 (0.57)
|
0.53 (0.20) [0.22,1.01]
|
|
Energy & Fatigue
|
3.01 (0.80)a
|
0.28 (0.07)a
|
1.15 (0.90)
|
2.00 (0.91)a
|
0.85 (0.33) [0.33,1.63]
|
- In all models a path adjusted for study (Synergy, REFRESH) and baseline value of mediator, b path adjusted for study (Synergy, REFRESH) and baseline value of mediator and outcome. a indicates p < 0.05
