Fig. 3

Joint associations of categories of transport modes and genetic susceptibility with incident coronary heart disease. Hazard ratios of coronary heart disease along with the corresponding 95% confidence intervals were presented. Model was adjusted for age (underlying timescale), sex, body mass index, smoking (never, previous, current), alcohol intake (never, previous, currently <3 times/week, currently ≥3 times/week), salt intake (never/rarely, sometimes, usually, always), oily fish intake (never, <once per week, once per week, >once per week), coffee intake (cups per day), fruit and vegetable intake (a composite score based on fresh/dried fruit intake and raw/cooked vegetable intake), processed/red meat intake (days per week), Townsend Deprivation Index (an indicator of area-based socioeconomic status), sleep (≤5, 6, 7, 8 and ≥9hours per day), total leisure-time physical activity (minutes per day; based on walking, non-walking moderate physical activity and non-walking vigorous physical activity), blood-pressure-lowering medication use, cholesterol-lowering medication use, glucose-lowering medication use, genotyping array type and the first ten principal components of genetic ancestry. For overall transport, p-value for multiplicative interaction=0.475; and p-value for additive interaction=0.045. For non-commuting, p-value for multiplicative interaction=0.427; and p-value for additive interaction=0.003. For commuting, p-value for multiplicative interaction=0.280; and p-value for additive interaction=0.067