Fig. 4

Hazard ratios for all-cause mortality according to isotemporal substitution of 30 min sedentary behavior with equivalent durations of LPA or MVPA among people with prediabetes and diabetes. Low- and high-activity subgroups were determined by sample-weighted medians of total physical activity time (LPA and MVPA). Models omitted the sedentary behavior component and adjusted for age, sex, race/ethnicity, education level, family income-to-poverty ratio, smoking status, alcohol consumption, body mass index, glycosylated hemoglobin A1c level, total cholesterol level, high-density lipoprotein cholesterol level, prevalence of cardiovascular disease, prevalence of hypertension, prevalence of cancer, and total wear time. Diabetes duration and glucose-lowering medications were additionally adjusted for patients with diabetes. Sedentary time was defined as < 100 cpm, LPA as 100–2020 cpm, and MVPA as ≥ 2020 cpm. Boldface type indicates P <0.05. cpm, counts per minute; LPA, light-intensity physical activity; MVPA, moderate- to vigorous-intensity physical activity