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Table 2 Hazard ratios (95% CI) for all-cause mortality according to tertiles of sedentary time among people with prediabetes and diabetes

From: Replacing of sedentary behavior with physical activity and the risk of mortality in people with prediabetes and diabetes: a prospective cohort study

Characteristic

Sedentary behavior, h/day

P for trend

Per 60-min increment

Tertile 1

Tertile 2

Tertile 3

Prediabetes (N = 1242)

 Median (IQR)

6.3 (5.5, 6.9)

8.1 (7.8, 8.6)

9.9 (9.4, 10.9)

  

 No. of deaths/total

87/414

149/414

188/414

  

 Model 1

1.00 (ref)

1.11 (0.75, 1.64)

2.01 (1.38, 2.94)

0.001

1.25 (1.14, 1.36)

 Model 2

1.00 (ref)

1.16 (0.76, 1.76)

1.98 (1.33, 2.93)

0.001

1.24 (1.13, 1.34)

 Model 3

1.00 (ref)

1.09 (0.70, 1.69)

1.76 (1.19, 2.60)

0.003

1.19 (1.10, 1.30)

Diabetes (N = 1037)

 Median (IQR)

6.8 (6.0, 7.3)

8.5 (8.2, 8.9)

10.2 (9.7, 11.1)

  

 No. of deaths/total

127/346

156/345

210/346

  

 Model 1

1.00 (ref)

1.24 (0.85, 1.19)

1.84 (1.20, 2.82)

0.004

1.28 (1.16, 1.42)

 Model 2

1.00 (ref)

1.31 (0.92, 1.87)

1.80 (1.24, 2.62)

0.002

1.23 (1.12, 1.36)

 Model 3

1.00 (ref)

1.24 (0.88, 1.77)

1.76 (1.17, 2.65)

0.007

1.25 (1.12, 1.40)

  1. Model 1: Adjusted for age (10-year intervals), sex (female or male), race/ethnicity (non-Hispanic white, non-Hispanic black, Hispanic Mexican, or others), and total wear time (continuous);
  2. Model 2: model 1 adjustments + potential confounders;
  3. Model 3: model 2 adjustments + BMI (< 25.0, 25.0–29.9, or ≥ 30.0 kg/m2) and MVPA (continuous)
  4. Potential confounders include education level (less than high school, high school or equivalent, or college or above), family income-to-poverty ratio (< 1.0, 1.0–3.0, or ≥ 3.0), smoking status (never, former, or current smoker), alcohol consumption (yes or no), HbA1c level (continuous), TC level (continuous), HDL-C level (continuous), prevalence of CVD, hypertension, or cancer (yes or no). Diabetes duration (< 5 or ≥ 5 years) and glucose-lowering medications (insulin, oral antidiabetic agents only, or neither) were specifically adjusted for patients with diabetes
  5. Abbreviate: BMI body mass index, CVD cardiovascular disease, HbA1c glycated hemoglobin A1c; HDL-C high-density lipoprotein cholesterol, IQR interquartile range, MVPA moderate- to vigorous-intensity physical activity, TC total cholesterol
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International Journal of Behavioral Nutrition and Physical Activity

ISSN: 1479-5868

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