Physical activity and sleep pattern in relation to incident Parkinson’s disease: a cohort study

Table 2 Hazard ratios for the associations of healthy sleep category and physical activity with risk of Parkinson’s disease

PA*	Low	Medium	High
Events/person-y	402/721,692	1,042/1,994,946	552/1,214,446
Age and sex-adjusted [HR (95% CI)]	Reference	0.89 (0.80, 1.00)	0.72 (0.63, 0.82)
Multivariable-adjusted [HR (95% CI)]	Reference	0.91 (0.81, 1.02)	0.73 (0.64, 0.84)
Sleep pattern*	Poor	Ideal	-
Events/person-y	336/517,961	1,660/3,413,123
Age and sex-adjusted [HR (95% CI)]	Reference	0.77 (0.68, 0.87)
Multivariable-adjusted [HR (95% CI)]	Reference	0.78 (0.69, 0.87)

Multivariable model was adjusted for age, sex, ethnicity, Townsend deprivation index, smoking status, BMI, SBP, DBP, antihypertensive medication use, sedentary time, healthy diet score, alcohol consumption, coffee consumption, tea consumption, and diabetes
* PA and sleep pattern were mutually adjusted in the analyses
CI, confidence interval; HR, hazard ratio; PA, physical activity

ISSN: 1479-5868